Huberman Lab Folgen

In this episode, I discuss how hormones such as testosterone and estrogen and their derivatives impact the early development of the brain and body and their maturation. I review published data on environmental factors shown to powerfully alter hormone pathways in animals and humans and the effects of cannabis, alcohol and cell phones on testes, sperm, ovaries and hormones. I describe the predictable relationship between genes, beard growth and balding patterns, and the importance of estrogen for brain development in people of all chromosomal sexes. Finally, I discuss how the hormones we are exposed to in the womb shape the relative length of our finger digits, the sounds our ears make (yes you read that correctly), and how those correlate with people's self-reports of their sexual preferences. As always, basic information and tools are discussed. Read the full show notes for this episode at hubermanlab.com. Thank you to our sponsors AG1: https://athleticgreens.com/huberman LMNT: https://drinklmnt.com/hubermanlab Waking Up: https://www.wakingup.com/huberman Timestamps 00:00:00 Introduction   00:00:30 AG1, LMNT & Waking Up   00:06:47 Announcement: Mood Meter App Works Again   00:08:00 Maximizing Learning from the Podcast   00:10:00 New Non-Sleep Deep Rest Protocol, Spanish Subtitles   00:11:35 Sexual Differentiation: Hormones, Neurons & Behavior   00:14:15 Hormones Basics   00:15:26 Sperm Meets Egg, Chromosomal Sex, Gonadal Sex   00:17:50 Y Chromosome Inhibition of Feminization   00:19:00 Placenta Is An Endocrine (Hormone-Producing) Organ, Adrenal Testosterone   00:19:45 Hormonal Sex, Morphological Sex   00:21:04 Hormones Fast & Slow, Sex Steroids Can Turn On Genes   00:23:06 Masculinization, Feminization, Demasculinization, Defeminization   00:23:42 Primary Sexual Characteristics: DHT Drives Penis Development   00:27:03 Secondary Sexual Characteristics   00:27:43 Penis Sprouting: Guevedoces   00:31:25 Estrogen, NOT Testosterone, Masculinizes The Brain   00:33:15 Breast Development In Males: Aromatase; Puberty, & Steroids in Athletes   00:34:50 Estrogen Powerfully Controls Brain Development In All Individuals   00:35:19 Avoiding Hormonal Disruption In Children & Adults: Specific Oils, Creams, Etc.   00:39:00 Environmental Endocrine Disruptors, Sperm Count Decline, Vincloziline   00:44:20 Androgen Insensitivity Syndrome: Hormones Need Receptors, SARMS   00:48:41 Estrogen Establishes “Masculine” Brain Circuits, Testosterone   00:49:42 Cannabis, Alcohol: In Babies, Puberty & Adults   00:56:25 Cell Phone Technology: Effects On Hormones, Ovaries, & Testicles   01:02:33 Beards & Baldness Patterns Around the World, DHT, 5-alpha-reductase   01:06:39 Creatine & DHT/Hair Loss   01:08:20 Predicting Aging Rates By Pubertal Rates   01:10:04 Hyenas, Baseball, & Jumbo Clitorises: Androstenedione   01:14:26 Intersex Moles   01:15:40 Marijuana Plants, Pollens: Plant-To-Animal “Warfare”   01:20:08 Finger Length Ratios, Prenatal Hormone Exposure & Sexual Orientation   01:29:13 Brain Dimorphisms with Sexual Orientation   01:32:00 “Older Brother Effects”: Male Fetuses Might Change Mothers & Subsequent Brothers   01:35:06 The Path Forward & A Warning   01:35:55 Support & Your Questions   Disclaimer & Disclosures Learn more about your ad choices. Visit megaphone.fm/adchoices

In this episode, I discuss the biology of emotions and moods in the context of relationships. I focus on the science of how early infant-caregiver attachment, combined with adolescence and puberty shape our adult patterns of attachment. I explain the three universal aspects of emotions, the reality of right-brain versus left-brain personalities, and how the roots of adult attachment are also grounded in specific aspects of puberty. I review what factors determine when puberty starts and ends, and the role of oxytocin and other chemicals in controlling how we perceive and remember others. As always, I refer to various practical tools including new tools for understanding and predicting our emotions before they occur, and neurochemicals that shape human connection. Read the full show notes for this episode at hubermanlab.com. Thank you to our sponsors AG1 (Athletic Greens): https://athleticgreens.com/huberman LMNT: https://drinklmnt.com/hubermanlab Waking Up: https://www.wakingup.com/huberman Timestamps 00:00:00 Introduction   00:00:32 Sponsors: AG1, LMNT & Waking Up   00:05:10 Announcing New Cost-Free Resources: Captions, NSDR Link   00:07:40 Emotions: Subjective Yet Tractable   00:10:53 To Understand Your Emotions: Look At Infancy & Puberty   00:15:21 Your First Feeling Was Anxiety   00:17:36 What Are “Healthy Emotions”?   00:19:03 Digital Tool For Predicting Your Emotions: Mood Meter App   00:21:08 The Architecture Of A Feeling: (At Least) 3 Key Questions To Ask Yourself   00:24:00 You Are An Infant: Bonds & Predictions   00:27:57 Attachment Style Hinges On How You Handle Disappointment   00:32:40 “Glue Points” Of Emotional Bonds: Gaze, Voice, Affect, Touch, (& Written)   00:36:34 “Emotional Health”: Awareness of the Interoceptive-Exteroceptive Dynamic   00:37:50 An Exercise: Controlling Interoceptive-Exteroceptive Bias   00:42:19 Getting Out Of Your Head: The Attentional Aperture   00:46:59 Puberty: Biology & Emotions On Deliberate Overdrive   00:47:58 Bodyfat & Puberty: The Leptin Connection   00:50:34 Pheromones: Mates, Timing Puberty, Spontaneous Miscarriage   00:54:37 Kisspeptin: Robust Trigger Of Puberty & Performance Enhancing Agent   00:58:26 Neuroplasticity Of Emotions: Becoming Specialists & Testing Emotional Bonds   01:00:25 Testing Driving Brain Circuits For Emotion: Dispersal   01:07:48 Science-Based Recommendations for Adolescents and Teens: The Autonomy Buffet   01:11:05 “Right-Brain Versus Left-Brain People”: Facts Versus Lies   01:14:18 Left Brain = Language, Right Brain = Spatial Awareness   01:16:15 How To Recognize “Right Brain Activity” In Speech: Prosody   01:18:32 Oxytocin: The Molecule of Synchronizing States   01:20:09 Mirror Neurons: Are Not For “Empathy”, Maybe For Predicting Behavior   01:23:00 Promoting Trust & Monogamy   01:27:00 Ways To Increase Oxytocin   01:28:34 Vasopressin: Aphrodisiac, Non-Monogamy and Anti-Bed-Wetting Qualities   01:30:43 Bonding Bodies, Not Just Minds: Vagus Nerve, Depression Relief Via the Body   01:35:18 A Powerful Tool For Enhancing Range & Depth of Emotional Experience   01:36:43 MDMA and Other Psychedelic Compounds: Building A Framework   01:38:54 Roundup, Various Forms of Support   Disclaimer & Disclosures Learn more about your ad choices. Visit megaphone.fm/adchoices

This episode explains the science of motivation and drive. I describe how dopamine — a chemical we all make in our brain, underlies our desire for and pursuit of our goals, as well as our capacity to move and experience pleasure. I describe how we can leverage specific behaviors, reward schedules and dopamine-prolactin balance to help ensure we can maintain motivation and capacity for pleasure over the long term. I also discuss dopamine in the context of ADHD, craving and addiction, and some absolutely amazing results about specificity of drug effects based purely on belief. Read the full show notes for this episode at hubermanlab.com. Thank you to our sponsors AG1: https://athleticgreens.com/huberman LMNT: https://drinklmnt.com/hubermanlab Waking Up: https://www.wakingup.com/huberman Timestamps 00:00:00 Introduction   00:00:30 Sponsors: AG1, LMNT & Waking Up   00:04:22 Announcement: Spanish Subtitles   00:05:06 Emotions, Addiction & Mindset   00:06:22 Motivation & Movement: The Dopamine Connection   00:07:29 A Double-Edged Dopamine Blade   00:08:56 Dopamine Fundamentals: Precursor to Adrenalin   00:10:15 The Reward Pathway: An Accelerator & A Brake   00:12:10 Motivation = Pleasure Plus Pain   00:14:14 The Dopamine Staircase: Food, Sex, Nicotine, Cocaine, Amphetamine   00:16:15 Subjective Control of Dopamine Release   00:17:40 Social Media and Video Games   00:18:15 Addiction & Dopamine: Progressively Diminishing Returns   00:18:48 Novelty, Sensation-Seeking & Anticipation   00:20:15 Craving: Part Pain, Part Pleasure & Pain Always Prevails   00:23:11 Desire Scales With Pain: The Yearning Function   00:24:43 The Croissant Craving Circuit   00:25:45 “Here and Now” Molecules: Serotonin, Bliss & Raphe Nucleus   00:26:26 In Your Skin Or Out In the World   00:27:25 Cannabinoids Lethargy & Forgetfulness   00:28:15 The Almond Meditation   00:29:30 Drugs That Shift Exteroception Versus Interoception   00:30:36 Emotional Balance, Active & Passive Manipulation   00:32:36 Procrastination: Leveraging Stress, Breathing, Caffeine, L-Tyrosine, Prescription Drugs   00:37:04 When Enough Is Never Enough; How Dopamine Undermines Itself   00:38:58 Dopamine-Prolactin Dynamics: Sex, Reproduction & Refractory Periods   00:40:30 The Coolidge Effect: Novelty-Induced Suppression of Prolactin   00:42:22 Vitamin B6, Zinc As Mild Prolactin Inhibitors   00:43:25 Schizophrenia, Dopamine Hyperactivity and Side Effects of Anti-Dopaminergic Drugs   00:45:08 Prolactin, Post-Satisfaction “Lows” & Extending the Arc of Dopamine   00:48:00 The Chemistry of “I Won, But Now What?”   00:49:00 Healthy Emotional Development: Child and Parent   00:50:03 Never Say “Maybe” (Reward Prediction Error)   00:52:02 Surprise!   00:52:59 Are You Suppressing Your Drive and Motivation By Working Too Late?   00:54:50 Disambiguating Pleasure and Drive: Dopamine Makes Us Anti-Lazy   00:58:00 Beta-Phenylethylamine (PEA), & Acetyl L-Carnitine   01:00:00 Attention Deficit Disorders, Cal Newport Books, Impulsivity & Obesity   01:03:55 Leveraging Dopamine Schedules   01:05:22 Subjective Control of Dopamine and Drug Effects: The “Adderall” Experiment   01:09:03 Caffeine May Protect Dopamine Neurons, Methamphetamine Kills Them   01:10:57 Nicotine: Dopamine, Possible Neuroprotection, Prolactin Increase   01:11:53 Gambling, Intermittent Reinforcement, & Persistent Goal Seeking (Bad and Good)   01:14:14 Intermittent Halting of Celebration; Enjoy Your Wins, But Not All of Them   01:18:38 A Story Example of Intermittent Reward to Maintain Long-Term Drive and Motivation   01:21:25 Corrections & Notes About Spanish Captions & Other Languages Soon   01:24:00 Synthesis & Framework, Zero-Cost Support & A Note About Sponsors Disclaimer & Disclosures Learn more about your ad choices. Visit megaphone.fm/adchoices