Anthony Fauci Reflects On 40 Years Of HIV/AIDS Research
Every week, the Centers for Disease Control and Prevention (CDC) releases its regular report of the latest developments on emerging diseases—a living record documenting decades of medical history, known as the Morbidity and Mortality Weekly Report (MMWR). In May 1981, former MMWR editor Michael B. Gregg got a call about an unusual deadly pneumonia, seen in young gay men in Los Angeles. The tip was from epidemiologist Wayne Shandera, Epidemic Intelligence Service Officer for the Los Angeles County Department of Health. He described the cases of five men, ages 29 to 36, who had developed Pneumocystis carinii, a kind of pneumonia typically seen in cancer and immunosuppressed patients. These men were previously healthy, yet they struggled to fight off the illness with treatment. Two of the patients died. All five were gay.
Gregg didn’t know what to make of the cases, but he and CDC experts were compelled to publish the observations in the June 5, 1981 issue of MMWR. Soon after, clinicians around the country began to flag similar cases. The number of infected people rose, as did awareness of the strange collection of symptoms. That summer, the media ran stories about the mysterious disease; the New York Times ran the headline, “Rare Cancer Seen in 41 Homosexuals.” At that time, Ira was a science correspondent for NPR, and was in the thick of covering the nuances of the illness.
Today marks 40 years since the first official report on the HIV/AIDS epidemic in the United States, and the beginning of a long-puzzling medical mystery. “I was totally baffled, and did not know what was going on. I thought it was a fluke,” recalls Dr. Anthony Fauci, director of the National Institute of Allergy and Infectious Diseases, during an interview this week with Science Friday. Read more at sciencefriday.com.
Where Did Watermelon Come From?
You may think of watermelon as a red, sweet taste of summer. The watermelon itself is ancient—paintings have been found in Egyptian tombs depicting a large green-striped object resembling a watermelon next to grapes and other sweet, refreshing foods. But if you look at many of the melon’s biological cousins, its red, sweet pulp is nowhere to be found—most close relatives of the watermelon have white, often bitter flesh. So how did the modern watermelon become a favorite summer snack?
Back in the 1960s, Russian researchers suggested that one sweeter melon species found in south Sudan might have been a close relative of the modern watermelon. Now, a detailed genetic analysis of a handful of wild melon species, and 400 modern varieties of watermelon from around the world, has concluded that the Kordofan melon from Sudan is, in fact, the closest living relative of the watermelon.
Susanne Renner, an emeritus professor at the University of Munich and an honorary professor of biology at Washington University in St Louis, explains the work on the origins of the modern melon—and how knowing the history of the watermelon could lead to new varieties.
NASA Plans Two New Trips To Venus
This week, President Biden announced the U.S. will donate 75% of its unused COVID-19 vaccine doses to foreign countries via the COVAX global vaccine program. The U.S. has promised to promptly send it’s surplus to South and Central America, Asia, and Africa, where countries are experiencing major shortages.
Plus on Wednesday, NASA announced plans to launch not one, but two new missions to explore Venus by the end of 2030. It’s the first time the agency has devoted any mission to Venus in 30 years.
MIT Technology Review editor Amy Nordrum joins Ira to discuss the biggest science stories of the week.
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Covering the outer reaches of space to the tiniest microbes in our bodies, Science Friday is the source for entertaining and educational stories about science, technology, and other cool stuff.
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Folge vom 04.06.2021Fauci On 40 Years Of HIV/AIDS, Watermelon Origins, Venus Missions. June 4, 2021, Part 1
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Folge vom 28.05.2021Sand Sustainability, Jane Goodall, Morphing Pasta, Cicada Snacks. May 28, 2021, Part 2Shifting The Sand Business To Greener Practices Sand is one of the most in-demand natural materials on the planet—some 50 billion tons of sand and gravel are mined every year. It’s because the humble sand is a key ingredient in many materials, from concrete and asphalt to microchips and glass. But sand is also heavy, needed in large quantities, and costly to ship—meaning that in some regions, local demand for sand outstrips supply. A ‘sand mafia’ exists in parts of the globe, and in others, international conflicts have arisen over accusations of illicit cross-border beach theft.Dr. Aurora Torres, a postdoctoral researcher in Michigan State University’s Center for Systems Integration and Sustainability and at the Catholic University of Louvain, joins host John Dankosky to talk about ways to make the business of sand extraction more ecologically-friendly—from manufacturing sand via high-tech rock crushing machines to reducing demand by recycling construction materials. A Trip Back In Time With Jane Goodall On September 27, 2002, Ira sat down for his first interview with the pioneering conservationist and primatologist Jane Goodall, to hear about her life, work, and vision for our relationship with our environment. Goodall is the 2021 recipient of the prestigious Templeton Prize for her work with animals and her contributions to humanity. When this interview originally aired, Goodall was already 40 years distant from her initial breakthrough discovery of tool use in chimpanzees, was the subject of a newly released IMAX movie, and had just been named a UN Ambassador for Peace. Learn more about her in the latest Science Friday Rewind, a series exploring historic interviews and scientific discoveries captured in our audio archives. A Bowl Full Of Pasta Engineering When you walk down the pasta aisle at the supermarket, there are so many tasty choices: There’s the humble spaghetti, the tubes of ziti, the tiny shells, and the butterfly-like farfalle. But every pound of pasta is not created equal—some of the boxes pack mostly air.In recent work published in the journal Science Advances, Dr. Lining Yao of Carnegie Mellon’s Morphing Matter Lab and her colleagues discuss an innovative way to solve the problem of puffed-up pasta boxes: What if different pasta shapes could be flat-packed into containers like DIY IKEA furniture? The researchers developed a way to map out tiny grooves and ridges on the surface of a flat noodle sheet. When the pasta is cooked in hot water, it swells at different rates around the ridges and grooves, causing it to fold on its own into shapes such as boxes, rose-like flowers, and helix curls. Yao joins SciFri’s Charles Bergquist to talk about the research, and the challenges of making your dinnertime pasta plate into an origami craft project. How To Take A Bite Of The Brood X Cicada Swarm After 17 years underground, billions, maybe even trillions, of cicadas are finally emerging in a group that scientists are calling Brood X. The cicadas will mate and die all within about six weeks—filling the air with a collective hum, and leaving behind their exoskeletons. For some this might sound like a horror movie, but for Bun Lai, chef at Miya’s Sushi in Connecticut, he sees this as an opportunity for a sustainable snack. He talks about how to hunt and cook a cicada, and how they fit in as a sustainable food source. Subscribe to this podcast. Plus, to stay updated on all things science, sign up for Science Friday's newsletters.
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Folge vom 28.05.2021Vaccine Hesitancy, Colorado River Drought, Alternative Syrups. May 28, 2021, Part 1How Do We Overcome Vaccine Hesitancy? This Memorial Day weekend, many people will be traveling to the beach, hitting the road or socializing with friends—maskless—for the first time in over a year. As of this week, 50% of people over 18 are now fully vaccinated. Another 15 to 20% of people are taking a “wait and see” approach. Of those still on the fence, some are concerned about the vaccine’s side effects; others have a long standing mistrust of the institutions responsible for the vaccine rollout. In order to fully end the pandemic, public health officials will have to find a way to get the vaccine-hesitant on board. Dr. Gary Bennett, professor of psychology and global health at Duke University sheds light on the hurdles that must be overcome. And a new segment of the population can now receive the Pfizer vaccine: children 12 years and older, after the Centers for Disease Control and Prevention gave approval in mid-May. But many American parents don’t want their children vaccinated at all—including for measles or the flu. One recent report from this past April showed that over 30% of parents would wait to get their child vaccinated—nearly double the percentage of adults who were hesitant. Matthew Simonson, a doctoral candidate at Northwestern University and lead author on the report, joins us to break down the numbers. What Happens When The Colorado River Runs Dry? Dry conditions are the worst they’ve been in almost 20 years across the Colorado River watershed, which acts as the drinking and irrigation water supply for 40 million people in the American Southwest. As the latest round of federal forecasts for the river’s flow shows, it’s plausible, maybe even likely, that the situation could get much worse this year. Understanding and explaining the depth of the dryness is up to climate scientists throughout the basin. Read the full article at sciencefriday.com. Making Syrup From More Than Maple Trees Researchers at the University of New Hampshire are studying new ways to make syrup out of the northern forest—not from maple trees, but from beeches, birches, sycamores and more. They want to create new markets for an industry that, right now, depends on just one kind of tree—making it vulnerable to disease and climate change. At the tail end of maple sugaring season, other kinds of sap were still flowing freely in the woods of Lee. UNH researcher David Moore had sensors plugged into a stand of beech trees to measure that sap and the conditions helping produce it. “You can see I have three trees with sensors here that are all tied back to one data logger,” Moore said, pointing to the tubes and wires running from the beech trunks. Nearby, a bucket collected the resulting sap, while other equipment gathered weather data. Researchers say monocultures, like the all-maple syrup industry, are more at risk from climate change, pests and other unpredictable threats. So Moore sees untapped potential in other common species, like the American beech. It’s found throughout New Hampshire’s forests, farms and sugar bushes—almost like a tree weed. “If you can think of some economical use—if you can make syrup from them, that would be a nice way to actually generate a little profit from them,” Moore said. Read the full article at sciencefriday.com. Big Oil Reckons With Climate Change Depending on your perspective, Wednesday was a bad day to be an oil company, or a good day to be a climate activist. Three major oil companies had climate change pushed higher on their agendas: Shell was ordered by a Dutch court to cut its greenhouse gas emissions 45% by 2030; Chevron was told by its shareholders to reduce not just its emissions from oil production, but also those of its customers; and at Exxon’s annual shareholder meeting, a small advocacy firm managed to score two, and possibly three, spots on its board of directors. So where did these climate coups come from, and what could come next? Vox staff writer Umair Irfan talks to John Dankosky about this week’s wins for the planet, as well as the limits of such reforms. Plus other stories from the week, including Moderna’s promising COVID-19 vaccine results in adolescents aged 12-17, and President Biden’s call for more investigation into COVID-19’s origins. Subscribe to this podcast. Plus, to stay updated on all things science, sign up for Science Friday's newsletters.
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Folge vom 21.05.2021Cybersecurity, Baseball Physics, Opioid Trial. May 21, 2021, Part 2Americans’ Online Security Needs An Update Last week, all eyes were on the shutdown of a gas pipeline that delivered fuel to large portions of the Southeastern US. The shutdown was not due to a leak or planned pipeline maintenance, but to a ransomware attack that took billing computers at the pipeline operator offline. The attack had encrypted data on those computers, rendering the data unusable to the pipeline operator until they paid a ransom.In recent years, similar ransomware attacks have affected other significant industries, from computers in a hospital cancer clinic to the Irish health system. Cybersecurity specialist Katie Moussouris, founder and CEO of Luta Security, joins Ira to talk about what’s behind the rise of ransomware attacks, and what businesses need to do to lessen their risks. Among the causes, she says, are increasing availability of anonymous money transfers via cryptocurrency, nation-states that sometimes turn a blind eye to hacking activities, and businesses who grow quickly without expanding their security to match. In West Virginia, Opioid Distributors Are Finally On Trial A trial is underway in West Virginia against the nation’s three largest opioid distributors: Cardinal Health, AmerisourceBergen, and McKesson. The companies are accused of funneling massive amounts of painkillers to West Virginia communities, fueling the opioid crisis that has devastated parts of the region. By some measures, Cabell County has the worst drug overdose rate in the country, and its rate of overdose deaths is six times the national average. While the companies say the doctors who prescribed the pills are to blame, this trial is a community’s attempt to hold the massive companies accountable. The city of Huntington, West Virginia and the Cabell County Commission brought the case against the companies. Joining Ira to talk about this trial and what led up to it is Eric Eyre, investigative reporter at Mountain State Spotlight in Charleston, West Virginia. Eric won a 2017 Pulitzer Prize for his reporting on the opioid epidemic in West Virginia, and is the author of the book Death in Mud Lick: A Coal Country Fight Against the Drug Companies That Delivered the Opioid Epidemic. Video Game Skills May Make Better Surgeons The classic board game Operation—in which players try to use conductive tweezers to remove a patient’s funny bone and other ailing imaginary organs—may not be the best tool for training real life surgeons for the operating room. But according to a recent paper published in the journal Surgery, playing video games may have a benefit for training surgeons in specific medical fields. Arnav Gupta, a third-year medical student at the University of Ottawa and co-author of the study, told Ira that the largest benefits of gaming seemed to come in two specific areas. Gains seen in robotic surgery skills might be due to the similarity of the robotic controls to a game controller joystick. Improvements in laparoscopic surgery, where surgeons operate using instruments inserted through tubes in a thin slit in a patient, may increase doctors’ ability to translate images on a screen to three-dimensional movements. (The researchers didn’t see major improvements in other types of surgery.) Gupta discusses the research with Ira, as well as possible next steps for ways gaming could improve medical training. What A Rare Baseball Collision Tells Us About The Physics Of The Game Recently during a pre-game warmup, Phillies right fielder Bryce Harper was doing some batting practice when he hit a line drive to right field, and it collided with another ball in midair. It was an extremely rare event we’ll probably never see again. But if someone were to try and duplicate the collision, would physics work in their favor? Ira is joined by Rhatt Allain, assistant professor of physics at Southeastern Louisiana University and writer for Wired’s Dot Physics blog, for a quick back of the envelope discussion. Plus, baseball players and fans are learning more about the physics of the game—exit velocity and launch angle are now statistics that people can calculate and tally. Dr. Alan Nathan, professor emeritus of physics at University of Illinois and professional baseball consultant, talks about how physics is changing how America’s pastime is played. The Resonating Room Tones Of Composer Alvin Lucier Alvin Lucier is one of the giant figures in experimental, electronic and electro-acoustic music, known for “making the inaudible…audible.” Last week, he turned 90, and the celebration included a 27 hour marathon of his most famous piece, “I Am Sitting In A Room.” The piece, first recorded in 1969, is very simple in concept but deceptively complex. It consists of a short passage of text, read aloud in a room. That sound is recorded and then played back into that same room, picked up by the same microphone, over and over, until the room resonance renders the speech otherworldly and unintelligible. "I Am Sitting In A Room" has been performed around the world, and has even prompted a series of adaptations by YouTubers, including one who uploaded his video 1,000 times, resulting in bizarre video degradation over time. Lucier’s work has been academically studied for years, and presented and championed at MIT’s Media Lab in seminars devoted to the “quality of sound as experience.” Listen to his work and a SciFri Soundscape of the music. Subscribe to this podcast. Plus, to stay updated on all things science, sign up for Science Friday's newsletters.