Science Friday Folgen

Can Fungus Survive Climate Change? One of the most extensive global networks for sharing information and moving around essential nutrients is hidden from us—but it’s right below our feet.  Networks of fungi often connect trees and plants to one another. But scientists are just starting to untangle what these fungal connections look like, and how important they are. Mycologist Christopher Fernandez explains how these fungal systems might be affected by climate change—and what that means for the entire forest ecosystem. A Cellular Race Through A Maze Cells are the basic building blocks of life. Our bodies are made up of trillions and trillions of them, and they all serve a specific purpose. But these tiny workers don’t always stay in the same place. Many move around the body—whether they’re creating a developing embryo, helping the immune system, or, distressingly, spreading cancer.   A team of scientists in the UK recently set up an experiment to learn more about how cells move. They put dirt-dwelling amoebas and mouse cancer cells at the start of a maze, to see how well each would migrate.  While amoebas proved speedier than their cancerous counterparts, Luke Tweedy, a postdoctoral researcher at the Beatson Institute for Cancer Research in Glasgow, Scotland, says the cancer cells were surprisingly mobile.  Tweedy joins Ira to talk about what his team learned about cancer cell movement, and explains why recreating a famous English hedge maze proved to be a little too difficult for his cellular subjects.  Fact Check Your Feed: Are Kids Really COVID-19 ‘Super Spreaders’? Late last month, as parents and teachers were gearing up for an unusual and stressful start to the school year, conflicting media reports of coronavirus transmission among children started populating our news feeds. One headline proclaimed, “New study suggests children may be COVID-19 ‘super spreaders,’” while other articles cited researchers saying the opposite. But the disagreement didn’t stop there. Some outlets reported that very few preschoolers are catching the coronavirus, while others cited a study that suggests children younger than 5 may harbor up to 100 times as much of the virus as adults. Angela Rasmussen, associate professor in the Columbia University Mailman School of Public Health, joins Ira to talk about the data behind these stories in a round of Fact Check Your Feed. She also explains new testing guidelines issued by the CDC, and a misleading report on the coronavirus death rate.  Subscribe to this podcast. Plus, to stay updated on all things science, sign up for Science Friday's newsletters.

New York City’s skyline is dominated by tall skyscrapers—but there’s a surprising amount of forest in the city known as a concrete jungle. Tree canopy actually covers about 20% of the city. In fact, woodlands are one of the few natural resources the city has. Reporter Clarisa Diaz, in collaboration with John Upton from Climate Central, shares how the city’s green spaces, both large and small, are needed to create an urban forest ecosystem in the face of climate change. Plus, forester David Nowak talks about the science behind planting an urban forest, and how to determine the value of a tree. Plus, while all eyes are currently on the COVID-19 pandemic, the coronavirus isn’t the only disease circulating the world. Lockdowns have hindered access to medical care, and supply chains for both tests and medications have been disrupted. With countries allocating limited public health resources to battle COVID-19, longstanding public health threats like tuberculosis, malaria, and HIV/AIDS may be at risk of resurging. However, there is also hopeful news for communities facing HIV/AIDS. Last week, a study published in the journal Nature examined 64 unusual people who seem to be able to naturally keep HIV at bay. Researchers investigated what makes these so-called ‘elite controllers’ able to manage their infections. They now think powerful T cells—a type of white blood cell which helps regulate the immune system—may hold a clue to these cases. Furthermore, earlier in the summer, a trial of a long-lasting injectable drug to prevent HIV infection was found to be at least as protective as the existing “pre-exposure prophylaxis,” or PrEP drug, which must be taken daily. Health and science reporters Apoorva Mandavilli of the New York Times and Jon Cohen of Science join Ira to discuss recent HIV/AIDS developments, and to reflect on 40 years of AIDS research.  Subscribe to this podcast. Plus, to stay updated on all things science, sign up for Science Friday's newsletters.

Recently, a group of scientists studying the Milky Way through the world’s largest ground-based radio telescope identified something they had never seen—a cold, dense gas that had been ejected at high speed from the galaxy’s center. The mystery of this gas—what caused it, how it could move so fast, and where it will end up—prompted research by Enrico Di Teodoro, a scientist in the department of astrophysics at Johns Hopkins University. He joined Science Friday producer Katie Feather to talk about the new discovery, as well as answer some fundamental questions about what is happening at the center of our galaxy. Plus, this year, back-to-school season comes with some major challenges to keeping students and teachers safe. Recently, New York City Mayor Bill DeBlasio announced a plan to give K-12 classes the option to move outdoors; the idea is that an open space, with a fresh breeze, lessens the chance of spreading the coronavirus. We’ve been brain-storming, too: What if you could bring the benefits of the outdoors inside, by creating better ventilation in the classrooms, akin to outside winds? What would it take to re-design or modify a typical classroom—not to mention your office building or home? Most modern buildings ventilate space with 80% recycled indoor air, and 20% of fresh outdoor air, to save on energy costs. But Shelly Miller, professor of mechanical engineering at University of Colorado, Boulder says, “In a pandemic, we don’t care about energy efficiency.” Miller explains that to lower the risk of infection, ideally indoor spaces would be ventilated with 100% outdoor air—but most building HVAC systems aren’t strong enough to handle that. Miller joins Jose-Luis Jimenez, professor in the department of chemistry and biochemistry at University of Colorado, Boulder to discuss what we know about the coronavirus, and our indoor air space and how we could build safer, healthier indoor spaces for the future. And cancer immunotherapy, especially a type known as checkpoint inhibitors, has given new hope to many people with cancer. The treatment takes the brakes off the body’s own immune system, allowing it to attack tumor cells. But some people respond to the therapy, while others don’t—and it’s not entirely clear why. In recent years, researchers have been looking into the microbiome—the collection of microorganisms that live in and on your body—for clues. Studies have found that there’s a microbial difference between people who respond to immunotherapy, and those who don’t. Research recently published in the academic journal Science, suggests scientists may have finally unraveled how one of those bacteria has an effect. The researchers discovered that Bifidobacterium pseudolongum, a species of bacteria found in elevated levels in the tumors of mice who responded well to immunotherapy, produces a small molecule called inosine—and that under the right conditions, inosine can help to turn on the immune T cells needed to attack a cancerous tumor. Kathy McCoy, one of the authors of the study, and the director of the IMC Germ-Free Program at the University of Calgary, joins Ira to talk about the study, and the challenges of raising mice without any microbiome at all.     Subscribe to this podcast. Plus, to stay updated on all things science, sign up for Science Friday's newsletters.