Psilocybin Effective In Treating Serious Depression
Depression is often treatable with medication, therapy, or a combination of the two. But some 30% of patients don’t respond well to existing medications—and may try multiple antidepressant drugs with little or no improvement.
This week, researchers reported that a new trial suggests psychedelics may be an effective therapy for treatment-resistant depression. A randomized, controlled, double-blind trial found that people with treatment-resistant depression who were given 25 milligrams of psilocybin, the psychedelic component of magic mushrooms, had a significant decrease in depressive symptoms. The treatment didn’t work for everyone, however, and more research needs to be done before the finding can move to clinical use.
Sabrina Imber, a science fellow at the New York Times, joins Ira to talk about the trial and other stories from the week in science—including a new timeline for the planned Artemis missions to the moon, screaming bees, and a very wayward eagle.
Activists And Vulnerable Nations At COP26 Seek More Than Promises
There’s a big international climate summit wrapping up in Glasgow, Scotland this week. COP26 is the followup to 25 previous United Nations meetings about how the world must respond to the climate crisis—and its shortcomings in doing so. This year leaders had a big conversation to tackle: Countries needed to pledge to reduce emissions even further to prevent a global temperature rise of more than 1.5 degrees Celsius. To do so, they needed to finish hashing out the details of how they will enforce the 2015 Paris Agreement’s provisions.
Meanwhile, island nations and other vulnerable countries, who themselves don’t emit much carbon, have continued to lobby for payment for what’s called loss and damages. That’s the harm they’ve already encountered as seas rise, threatening to obliterate their existence.
The first week kicked off with bold pledges about methane emissions, coal phaseouts, and ending deforestation. This week, former President Obama spoke about the need for urgent action, and called out large greenhouse gas polluters like Russia and China for not attending. And a grim United Nations report was released, forecasting that despite all the bold pledges, the world was on track to warm a dangerous 2.4 degrees Celsius. The team of Threshold, a podcast that tells stories about our changing environment, has been reporting on these updates from Glasgow, talking to attendees and occasionally witnessing negotiations.
In today’s show, Ira talks to journalist Amy Martin, Threshold’s executive producer and host, about her opinion on the outcome of COP26—and if transformative change can still come out of this year’s meeting.
”Dopesick” Takes On The Opioid Crisis
The opioid epidemic has affected millions of people across the country—and more than 800,000 people are estimated to have died from an opioid overdose. At the root of this crisis is the painkiller Oxycontin, manufactured by Purdue Pharma.
The company has made billions of dollars from the drug; but has also spent the better part of the last two decades fighting legal battles over its impacts, falsely arguing the drug is non-addictive and completely safe. Meanwhile, people from all walks of life, particularly in small towns across America, have been crippled by addiction to Oxycontin.
The limited series “Dopesick” traces the story of the opioid epidemic, from the creation of the Oxycontin pill to a landmark legal battle where Purdue Pharma admitted it misbranded the drug as being less addictive than other prescription opioids.
“Dopesick” follows a wide range of characters, from Purdue Pharma executives and federal prosecutors, to an Appalachian doctor and his pain-addled patients. Joining Ira to talk about bringing the show and its people to life is Danny Strong, creator and writer of “Dopesick,” joining from New York, New York.
Subscribe to this podcast. Follow our show on Instagram, TikTok, Facebook, and Bluesky @scifri and sign up for our newsletters. Got a science question that’s keeping you up at night? Call us: 877-472-4374 Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.
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Covering the outer reaches of space to the tiniest microbes in our bodies, Science Friday is the source for entertaining and educational stories about science, technology, and other cool stuff.
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Folge vom 12.11.2021Psychedelics Can Treat Depression, Climate Meeting, Dopesick Show. Nov 12 2021, Part 1
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Folge vom 06.11.2021Kids Under 12 Vaccine, Reduced Cow Methane From Seaweed Diet, Lost SciFri Theme Song. November 5, 2021, Part 2Fact Check My Feed: More Kids Can Get COVID-19 Vaccines. Now What? Many parents around the U.S. breathed a sigh of relief—or an even more intense emotional reaction—at the long-awaited news that the Centers for Disease Control and Prevention (CDC) had signed off on advising the Pfizer-BioNTech COVID-19 vaccine for children aged 5 to 11 this week. The recommendation came after a unanimous vote from the agency’s committee of outside vaccine experts. And last week, the Food and Drug Administration (FDA) authorized the shot after a review of clinical trial data found both low risk and high efficacy in a smaller, kid-calibrated dose of the vaccine. University of Saskatchewan virologist Angela Rasmussen joins Ira to look at the data behind the FDA’s long-anticipated decision. They also discuss the rationale behind booster shots for high-risk adults, what it means that deer in Iowa have been caught transmitting the virus, COVID-pragmatic holiday planning, and other pandemic news. In First Real-World Experiment, Red Seaweed Cuts Methane In Cows By More Than Half Methane emissions are a hot topic—largely because it’s a big contributor to climate change. Methane makes up about 10% of human-caused greenhouse gas emissions. 27% of that comes from the burps of ruminant animals, such as cows. In April, Science Friday did a story about research that showed promising results when steers were fed small amounts of the red algae Asparagopsis in their diets. At the time, these experiments were only done in a closely controlled university setting. Now, the first real-world study on a working dairy farm has been completed. The results? Methane released by the seaweed-eating cows was 52% less on average than their non-seaweed-munching counterparts. Coming on the heels of the Biden administration’s methane emissions reduction plan, SciFri producer Kathleen Davis sits down with three key players in this milestone: Joan Salwen, CEO of Blue Ocean Barns in Kailua-Kona, Hawaii, the company that produces the Asparagopsis seaweed powder; Dr. Breanna Roque, animal science consultant at Blue Ocean Barns in Townsville, Queensland, Australia; and Albert Straus, founder and CEO of Straus Family Creamery in Marshall, California. The Science Friday Theme Song That Got Lost In The Mail Back in 1998, comedian and author Steve Allen, first host of The Tonight Show, joined Ira on Science Friday to talk about the importance of critical thinking. Allen had written a book called Dumbth, calling for improvements in the public’s logical reasoning abilities. Ira was a longtime fan of Allen’s, and eagerly invited him to discuss the book. During the interview, Allen also took to the studio piano to play his signature song, “This Could Be The Start of Something Big.” As the comedian was leaving, Ira jokingly remarked that Science Friday could use a theme song of its own. Several years later, while cleaning the cluttered SciFri office, staff uncovered an unopened box of mail—including an envelope from Hollywood containing a single cassette tape, marked “Theme Song For Science Friday—Steve Allen.” As part of Science Friday’s 30th anniversary celebrations, Ira and SciFri director Charles Bergquist recount the story of the tape, and finally premiere the song, written and performed by the late Steve Allen. Subscribe to this podcast. Follow our show on Instagram, TikTok, Facebook, and Bluesky @scifri and sign up for our newsletters. Got a science question that’s keeping you up at night? Call us: 877-472-4374 Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.
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Folge vom 06.11.202130 Years Of Science Friday, Kansas’ Wind Energy Plan, Vaccinating Kids Under 12. November 5, 2021, Part 1Behind The FDA’s Decision To Vaccinate Kids Under 12 This week, Pfizer’s COVID-19 vaccine for kids under 12 was officially recommended by the CDC, after a unanimous vote from its independent advisory committee and the FDA’s authorization based on safety and efficacy data. In their analysis, the FDA said the benefits of the vaccine “clearly outweigh” the risks. The risks, which were referenced in a cost-benefit examination of the data, included circumstances that popped up in the study that were unrelated to getting the vaccine (like a broken arm and an accidentally swallowed penny that occurred during the observational period). As parents around the U.S. race to find appointments, Ira talks to science journalist Maggie Koerth about the safety data and what’s next for parents of young kids, including those under 5. They also discuss a NASA test of a system to defend the planet from killer asteroids, a new prediction that climate change will change the availability of food crops within the next ten years, and other science news headlines. What’s Next For Kansas After 20 Years Of Wind Power? The wind farm business in Kansas has hit its awkward adolescence. It’s still growing 20 years in, but unsure what the near future might hold. If it wants to get through those tough years and continue to grow, it needs to find more workers, to figure out what to do with the dated-but-not-obsolete turbines erected two decades ago and to sort out a way to carry all that wind-harvesting muscle beyond the state’s borders. Consider the burly, newest version of wind farming at the Cimarron Bend wind farm south of Dodge City. “We just watch and listen to the towers,” said project supervisor Dewain Pfaff, who’s responsible for keeping about 300 turbines up and running. “If you can hear a noise we want to mitigate those issues as soon as possible.” Standing at the base of one of the newest turbines on the site, he’s dwarfed by the tower that rises 300 feet into the air. That’s almost as tall as the Kansas State Capitol. Add in the blade when pointing straight up and it’s taller than the tallest building in the state. That mammoth size is one way wind turbines have changed over the past 20 years. While the turbine is nearly 300 feet tall, the turbines at the very first large-scale wind farm in the state stretched only 200 feet above the ground. Transporting larger towers and blades is trickier, but inevitable. Read the rest at sciencefriday.com. SciFri Reflects On Three Decades Of Covering Science News Thirty years ago this week, on Nov 8, 1991, the first episode of Science Friday aired as part of NPR’s “Talk of the Nation” series. After 30 years, over 9,000 interviews, and several changes of distributors, offices, and studios, the program is still going strong. In this segment, host and executive producer Ira Flatow and SciFri director Charles Bergquist reminisce about some of the great guests and listener questions they’ve heard over the course of the program—from the very first episode, featuring the late Nobel Laureate Sherwood Rowland talking about the ozone hole, to a young fan helping to celebrate SciFri’s Cephalopod Week with her own ode to an octopus. Plus, moments with Jane Goodall, Sylvia Earle, astronaut Leland Melvin, the late Carl Sagan, and more. Subscribe to this podcast. Follow our show on Instagram, TikTok, Facebook, and Bluesky @scifri and sign up for our newsletters. Got a science question that’s keeping you up at night? Call us: 877-472-4374 Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.
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Folge vom 29.10.2021Kids Next For Pfizer Vaccine, Side-Channel Surveillance, Medical Maggots. Oct 29, 2021, Part 1Younger Kids Next In Line For COVID-19 Vaccines This week, an FDA advisory panel voted unanimously to recommend that the COVID-19 vaccine made by Pfizer vaccine be approved for children as young as 5. If the FDA concurs and the CDC agrees, lower-dose Pfizer vaccinations could soon be available for children ages 5 to 11, via local pediatricians. Just who will be immediately eligible for the doses, and how vaccinating young children might affect school mask policies and other restrictions, remains to be seen. Umair Irfan, staff writer at Vox, joins Sophie Bushwick to talk about the news and other stories from the week in science, including potential COVID-related criminal charges against Brazil’s Jair Bolsonaro, an experimental bionic vision implant, and the possible discovery of an exoplanet in the galaxy Messier 51. Could Ordinary Household Objects Be Used To Spy On You? In the movies, if a room is bugged, the microphone might be hidden in a potted plant. But in recent years, researchers have come up with ways to use the trembling leaves of a potted plant, light glancing off a potato chip bag, and even tiny jiggles in the head of a spinning hard drive caused by a nearby conversation to be able to listen to what’s happening in a room, or to gain information about what’s going on nearby. On a larger scale, other researchers have been able to use the vibrations of an entire building to paint a picture of movements within it—and even the health status of the people inside. The approach is known as a side-channel attack: Rather than observing something directly, you’re extracting information from something else that has a relationship with the target. Many of the approaches are not straightforward—they require an understanding of the physics involved, and sometimes heavy data-processing or machine learning to interpret the hazy information yielded by these techniques. Jon Callas of the Electronic Frontier Foundation, Hae Young Noh of Stanford, and Kevin Fu of the University of Michigan join host Sophie Bushwick to talk about the risks and opportunities afforded by these sneaky methods of surveillance, and how concerned you should be. A Maggot Revolution In Modern Medicine In a bloody battle during World War I, two wounded soldiers were stranded on the battlefield in France, hidden and overlooked under some brush. Suffering femur fractures and flesh wounds around their scrotum and abdomen, they lay abandoned without water, food, or shelter for a whole week. At the time, outcomes for these kinds of wounds were poor: Patients with compound femur fractures had a 75 to 80% mortality rate. By the time the soldiers were rescued and brought to a hospital base, orthopedic surgeon William Baer expected their wounds to be festering, and their conditions fatal. But much to his surprise, neither showed any signs of fever, septicaemia, or blood poisoning. When his team removed the soldiers’ clothing, they discovered that their flesh wounds were filled with thousands of maggots, or baby flies—little larvae with a massive appetite for decaying matter. Baer was repulsed by the sight, and the team quickly washed off the wriggling maggots. Underneath, instead of the expected pus and bacteria-infected flesh, Baer marveled over “the most remarkable picture.” “These wounds were filled with the most beautiful pink granulation tissue that one could imagine,” Baer later wrote in a 1931 report in the Journal of Bone and Joint Surgery. Maggots have long been associated with death, but in this case, they were helping the soldiers stay alive. As these insects were simply tucking in for their typical meal of dead, decaying flesh, they were inadvertently aiding the soldiers by cleaning their wounds, keeping infection at bay. The soldiers recovered—saved by their tiny, wriggling “friends which had been doing such noble work,” Baer wrote. Baer’s paper is one of the first reports of maggots used in medicine, but these insects have been found healing wounds for thousands of years, with references in the Old Testament and in ancient cultures of New South Wales and Northern Myanmar. Read the rest on sciencefriday.com. Subscribe to this podcast. Follow our show on Instagram, TikTok, Facebook, and Bluesky @scifri and sign up for our newsletters. Got a science question that’s keeping you up at night? Call us: 877-472-4374 Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.