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Biochemist Kati Karikó spent decades experimenting with mRNA, convinced that she could solve the problems that had kept it from being used as a therapeutic. Her tireless, methodical work was dismissed and she was ridiculed. But that work laid the foundation for the rapid development of COVID-19 vaccines that saved millions of lives, and was recognized by a Nobel Prize in 2023. Kati shares her secret weapon for dealing with stress and naysayers. Plus, neurologist David Langer describes Kati’s exacting research style, and her daughter, Olympic gold medalist Susan Francia, reveals the life lessons that led them both to the winner’s circle.“The Leap” is a 10-episode audio series that profiles scientists willing to take big risks to push the boundaries of discovery. It premieres on Science Friday’s podcast feed every Monday until July 21. “The Leap” is a production of the Hypothesis Fund, brought to you in partnership with Science Friday.Transcript will be available after the show airs on sciencefriday.com. Subscribe to this podcast. Plus, to stay updated on all things science, sign up for Science Friday's newsletters.

Proposed budget cuts for NASA would jeopardize space research. And an executive order could change the political tides for deep sea mining.On May 2, the Trump Administration proposed a 24% budget cut for NASA. It would slash funding for science while setting billions aside for initiatives to send humans to the moon and Mars. New Scientist editor Sophie Bushwick joins us to talk about this, as well as other news in science, like how many U.S. cities are sinking, the search for geologic hydrogen within mountains, the first photos of free-floating atoms, Chinese poetry about porpoises, and cicadas turned into speakers.And, President Trump recently issued an executive order that would fast-track access for deep sea mining. Soon after, a Canadian company called The Metals Company submitted the first application for NOAA to review. This has raised environmental and climate concerns, as well as geopolitical tensions. Ocean geologist Sandor Mulsow breaks down what’s at stake for the ocean.Guests:Sophie Bushwick, senior news editor at New Scientist in NYCDr. Sandor Mulsow, marine geologist at the Austral University of ChileTranscript will be available after the show airs on sciencefriday.com.  Subscribe to this podcast. Plus, to stay updated on all things science, sign up for Science Friday's newsletters.

Bacteria have been around for billions of years. Could they have come up with complex behaviors that we just don’t understand yet? Could they have their own language? Their own culture? Their own complex societies playing out right under, and in, our noses? Microbiologist Bonnie Bassler has been studying these questions for more than 30 years. She talks with Host Flora Lichtman about the wild world of bacterial communication, and how understanding microbes could help us understand ourselves.Guest: Dr. Bonnie Bassler, microbiologist at Princeton UniversityTranscript will be available after the show airs on sciencefriday.com. Subscribe to this podcast. Plus, to stay updated on all things science, sign up for Science Friday's newsletters.