Although vaccines will go a long way to reducing the number of cases of Covid, there’s still a need for other approaches. One of these could be an engineered biomolecule, designed by virologists Anne Moscona and Matteo Porotto, that blocks SARS-CoV-2 precisely at the moment it tries to enter cells in the nose and upper airways. Roland Pease talks to Anne Moscona about this “molecular mask”. We’re already beginning to see really encouraging analyses showing that Covid vaccines are performing as well in the real world as was promised by last year’s trials. Shane Crotty of the La Jolla Institute for Immunology discusses progress so far and the question of one dose or two with Roland. Lives can be saved if there’s an early warning system for earthquakes and tsunamis. Seismologist Zhongwen Zhan at CalTech has been experimenting with a newly installed 10,000 km cable laid along the Pacific coasts of north and south America by Google, all the way from Los Angeles to Santiago. What he was looking for were subtle changes in a property of light that’s important to IT engineers, and can detect subsea earthquakes.We are still sending too much waste to landfill sites. At the Commonwealth Science Conference this week Veena Sahajwalla of the University of New South Wales explained how she is creating small scale factories that can use discarded objects such as ceramics and textiles to make new products. (Image: Getty Images)
Presenter: Roland Pease
Producer: Deborah Cohen
Folgen von Science In Action
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Folge vom 25.02.2021Waste not, want not
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Folge vom 18.02.2021Weird weatherA paper in the BMJ shows that deaths from Covid 9 are being massively overlooked in Zambia. The new data come from post-mortem tests at the University Hospital mortuary in Lusaka, showing that at least 1 in 6 deaths there are due to the coronavirus; many of the victims had also been suffering from tuberculosis. Chris Gill of Boston University’s Department of Global Health, and Lawrence Mwananyanda, chief scientific officer of Right to Care, Zambia, discuss their findings with Roland Pease. New variants of concern continue to be reported, such as the one labelled B 1 1 7 in the UK, or B 1 351 identified in South Africa. Geneticist Emma Hodcroft, of the University of Bern, talks about seven variants that have been found in the US. Although all these variants are evolving from different starting points, certain individual mutations keep recurring – which suggests they have specific advantages for the virus. Her co-author Jeremy Kamil, of Louisiana State University Health Sciences Center in Shreveport, explains how he can watch the viruses replicating inside cells. Much of the United States, as far south as Texas, and Eurasia, has been gripped by an extraordinary blast of Arctic weather. Roland hears from climatalogist Jennifer Francis, of the Woodwell Climate Research Center, about the Arctic’s role in this weird weather. Life, in the form of sponges, has been discovered hundreds of metres under the thick ice surrounding Antarctica, where it’s dark, subzero and barren. The British Antarctic Survey’s Huw Griffiths reveals how it was spotted unexpectedly in pictures colleagues took with a sub-glacial camera.(Image: A man walks to his friend's home in a neighborhood without electricity as snow covers the BlackHawk neighborhood in Pflugerville, Texas, U.S. Credit: Reuters) Presenter: Roland Pease Producer: Deborah Cohen
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Folge vom 11.02.2021Perseverance approaches MarsOn 18th February the Perseverance rover should land on Mars. Katie Stack-Morgan of NASA’s Jet Propulsion Lab tells Roland Pease about the technological advances that mean that the spacecraft should be able to land in Jezero Crater. Imperial College geologist Sanjeev Gupta discusses what this crater can reveal about the history of life on the red planet. After months of negotiations, and weeks of work on the ground, a team brought together by the World Health Organisation has just concluded its first attempts to find out the origins of SARS-Cov2 in Wuhan. Peter Daszak, who has worked closely with Chinese virologists in the past, briefed Roland Pease on what had been discovered. The South African government has announced that it will not be rolling out the Astra Zeneca Covid vaccine as it appears it is not very effective against the dominant strain in the country. Helen Rees, of Witwatersrand University and a member of South Africa’s Health Products Regulatory Authority, explains that the ‘ban’ is an overstatement.At least 35 people died in a flood disaster in the Himalayan state of Uttarakhand in India on February 6th. The details are still unclear, but the trigger seems to be associated with a glacier overhanging an upstream lake in the steep valley. Rupert Stuart-Smith of Oxford University, who has just published an analysis of a glacier melting disaster in waiting in the Andes, talks about the impacts of climate change on the stability of mountain glaciers. (Image: An illustration of NASA’s Perseverance rover landing on Mars. Credit NASA/JPL-Caltech)
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Folge vom 04.02.2021Mixing Covid vaccinesA new trial is about to start in the UK, seeing if different vaccines can be mixed and matched in a two-dose schedule, and whether the timing matters. Governments want to know the answer as vaccines are in short supply. Oxford University’s Matthew Snape takes Roland Pease through the thinking. Despite the numbers of vaccines being approved for use we still need treatments for Covid-19. A team at the University of North Carolina is upgrading the kind of manufactured antibodies that have been used to treat patients during the pandemic, monoclonal antibodies. Lisa Gralinski explains how they are designing souped-up antibodies that’ll neutralise not just SARS-CoV-2, but a whole range of coronaviruses. Before global warming, the big ecological worry that exercised environmentalists was acid rain. We’d routinely see pictures of forests across the world dying because of the acid soaking they’d had poisoning the soil. In a way, this has been one of environmental activism’s success stories. The culprit was sulphur in coal and in forecourt fuels – which could be removed, with immediate effect on air quality. But biogeochemist Tobias Goldhammer of the Leibniz Institute in Berlin and colleagues have found that sulphur, from other sources, is still polluting water courses. There’s been debate over when and where dogs became man’s best friend. Geoff Marsh reports on new research from archaeology and genetics that puts the time at around 20,000 years ago and the place as Siberia. (Image: Getty Images) Presenter: Roland Pease Producer: Deborah Cohen