Could viruses improve our health where antibiotics have failed? As a child, Martha Clokie spent a lot of time collecting seaweed on Scottish beaches. She loves plants and studied botany for many years. But mid-career, she learnt about all the viruses that exist in nature. We tend to focus on the viruses that make us ill but there are trillions of viruses on earth and in the ocean and most of them eat bacteria. When a virus destroys a bacteria that attacks our bodies, then it could be just what the doctor ordered. Our enemy’s enemy is our friend. Martha became interested in how these viruses - or bacteriophages as they’re known - might be used to treat disease. Before long, Martha had moved from studying African violets in Uganda to looking at stool samples under the microscope and asking fellow parents to donate their babies’ dirty nappies to her research. She spent many years looking for phages that attack the superbug C. difficile, which is responsible for a particularly nasty form of diarrhoea and results in tens of thousands of deaths every year. And she has shown, in animal models at least, that these phages could succeed where antibiotics have failed.Producer: Anna Buckley

Wissenschaft & Technik
The Life Scientific Folgen
Professor Jim Al-Khalili talks to leading scientists about their life and work, finding out what inspires and motivates them and asking what their discoveries might do for us in the future
Folgen von The Life Scientific
332 Folgen
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Folge vom 15.10.2019Martha Clokie on the viruses that could improve our health
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Folge vom 08.10.2019Anne Magurran on how to measure biodiversityAnne Magurran started her career as an ecologist counting moths in an ancient woodland in northern Ireland in the 1970s, when the study of biological diversity was a very young science. Later she studied piranas in a flooded forest in the Amazon. Turning descriptions of the natural world into meaningful statistics is a challenge and Anne has pioneered the measurement of bio-diversity. It’s like an optical illusion, she says. The more you think about bio-diversity the more difficult it is to define. After a bout of meningitis in 2007, she set up BioTime, a global open access database to monitor changes in bio-diversity over time and is concerned about ‘the shopping mall effect’. Just as high streets are losing their distinctive shops and becoming dominated by the same chain stores, so biological communities in different parts of the world that once looked very different are now starting to look the same.
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Folge vom 01.10.2019Richard Wiseman on lying, luck and the paranormalHow do you tell if someone is lying? When Richard Wiseman, Professor of the Public Understanding of Psychology at the University of Hertfordshire, conducted a nationwide experiment to identify the tell-tale signs, the results were surprising. If you want to spot a liar, don’t look at them. Listen to what they say and how they say it. in If you want to distinguish fact from fiction, radio, not TV or video is your friend. Visual cues distract us from what is being said and good liars can control their body language more easily than their voice. Depressingly, Richard has also shown that our nearest and dearest are the most able to deceive us. Richard is a rare breed: a scientist who is also a practising magician. By the age of 17 he was performing magic tricks at children’s parties and a member of the exclusive Magic Circle. He chose to study psychology to try and understand why we believe the unbelievable and spent many years doing research on the paranormal: studying séances, haunted places and extra sensory perception. Could a belief in the paranormal be the price we pay for scientific discovery, he wonders? Jim Al-Khalili talks to Richard about his magical Life Scientific and finds out more about his work on lying, ESP and luck. Are some people born lucky or is it a mind-set that can be learnt? Producer: Anna Buckley
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Folge vom 30.07.2019Jonathan Ball on his arms race against virusesEbola, Zika, Sars, Mers - rarely a week goes by without a deadly virus stealing the headlines. For Jonathan Ball, getting to know a virus at its most basic level is crucial to mounting a defence. As the son of a coal miner, who grew up in a mining village in the 1970s, a future in academic research studying deadly viruses wasn’t really on the agenda. Yet his work has led him to the forefront of scientific research to find the antibodies that can protect us from some of the nastiest diseases known to humankind. As Professor of Virology at Nottingham University, he’s interested in how a virus evolves and mutates, as it moves from person to person, so that he can pinpoint chinks in its armour to find a way to disable it.However, there are occupational hazards to his chosen field of work. Just when his own research was starting to show promise, another team pipped him to the post! Yet, ever the optimist, he believes this just adds to the excitement.Producer: Beth Eastwood