Patrick Vallance is something of a rare breed: a game-keeper turned poacher; an academic who's moved over into industry. And not just any industry, but the pharmaceutical industry.At the time, Patrick Vallance was Professor of Clinical Pharmacology and Head of the Department of Medicine at University College London. A pioneer of research into some of the body's key regulatory systems, he had also been publicly critical of BIG Pharma for "funding studies more helpful to marketing than to advancing clinical care". So what made him go over to "the other side"?His involvement with the industry was limited until one evening in 2006 when he was asked a question over a dinner, a question that would be pivotal to his life and career. Today, Patrick is head of research and development at GlaxoSmithKline, one of the world's largest pharmaceutical companies with annual revenues in excess of 20 billion pounds and nearly a hundred thousand employees worldwide. Whilst GSK is no stranger to scandal, since he joined, Patrick has attempted to tackle the culture of secrecy that pervades the industry. He's since reshaped the way GSK carries out its research and has been behind several radical initiatives in global healthcare, to produce a more collaborative approach to tackling major diseases like malaria.
Wissenschaft & Technik
The Life Scientific Folgen
Professor Jim Al-Khalili talks to leading scientists about their life and work, finding out what inspires and motivates them and asking what their discoveries might do for us in the future
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Folge vom 03.11.2015Patrick Vallance on pharmaceuticals
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Folge vom 20.10.2015Robert Plomin on the genetics of intelligenceProfessor Robert Plomin talks to Jim Al-Khalili about what makes some people smarter than others and why he's fed up with the genetics of intelligence being ignored. Born and raised in Chicago, Robert sat countless intelligence tests at his inner city Catholic school. College was an attractive option mainly because it seemed to pay well. Now he's one of the most cited psychologists in the world. He specialized in behavioural genetics in the mid seventies when the focus in mainstream psychology was very much on our nurture rather than our nature, and genetics was virtually taboo. But he persisted, conducting several large adoption studies and later twin studies. In 1995 he launched the biggest longitudinal twin study in the UK, the TED study of ten thousand pairs of twins which continues to this day. In this study and in his other work, he's shown consistently that genetic influences on intelligence are highly significant, much more so than what school you go to, your teachers or home environment. If only the genetic differences between children were fully acknowledged, he believes education could be transformed and parents might stop giving themselves such a hard time. Producer: Anna Buckley.
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Folge vom 13.10.2015Danielle George on electronicsDanielle George is a radio frequency engineer from the University of Manchester. She designs amplifiers that have travelled everywhere, from outer space to underground.Becoming a professor aged just 38, she talks to Jim about the challenges of age discrimination and working in a male dominated field.As presenter of last year's Royal Institution Christmas Lectures, she's passionate about DIY electronics and coding, and how to inspire the UK's next generation of inventors.
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Folge vom 06.10.2015Dame Carol Black on public healthCarol Black was an overweight child who, aged 13, put herself on a diet. Now, as an expert advisor to the government, she's the woman behind recent newspaper headlines suggesting that obese people who refuse treatment could see their benefits cut. In the last decade, Carol has conducted several reviews on work and health, sickness absence and how best to help people with obesity, alcohol and drug problems get back into the workplace. In 2008 she suggested the Sick Note should be replaced with a Fit Note which states what people can do rather than what they can't. Later she recommended that an independent assessor should decide who is, or is not, Fit for Work. Dame Carol Black talks to Jim Al-Khalili about the challenges associated with advising government on these controversial issues; and how, despite relative adversity and several bad decisions, she achieved such a position of power and influence.Producer: Anna Buckley.