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The Huberman Lab podcast is hosted by Andrew Huberman, Ph.D., a neuroscientist and tenured professor in the department of neurobiology, and by courtesy, psychiatry and behavioral sciences at Stanford School of Medicine. The podcast discusses neuroscience and science-based tools, including how our brain and its connections with the organs of our body control our perceptions, our behaviors, and our health, as well as existing and emerging tools for measuring and changing how our nervous system works. Huberman has made numerous significant contributions to the fields of brain development, brain function, and neural plasticity, which is the ability of our nervous system to rewire and learn new behaviors, skills, and cognitive functioning. He is a McKnight Foundation and Pew Foundation Fellow and was awarded the Cogan Award, given to the scientist making the most significant discoveries in the study of vision, in 2017. Work from the Huberman Laboratory at Stanford School of Medicine has been published in top journals, including Nature, Science, and Cell, and has been featured in TIME, BBC, Scientific American, Discover, and other top media outlets. In 2021, Dr. Huberman launched the Huberman Lab podcast. The podcast is frequently ranked in the top 10 of all podcasts globally and is often ranked #1 in the categories of Science, Education, and Health & Fitness.
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Folge vom 01.02.2024AMA #15: Fluoride Benefits/Risks & Vagus Nerve StimulationWelcome to a preview of the 15th Ask Me Anything (AMA) episode, part of Huberman Lab Premium. Huberman Lab Premium was launched for two main reasons. First, it was launched in order to raise support for the main Huberman Lab podcast — which will continue to come out every Monday at zero-cost. Second, it was launched as a means to raise funds for important scientific research. A significant portion of proceeds from the Huberman Lab Premium subscription will fund human research (not animal models) selected by Dr. Huberman, with a dollar-for-dollar match from the Tiny Foundation. Read our Annual Letter 2023. If you're an existing Premium member, you can login to access the full episode. If you're not a member, you can join Huberman Lab Premium to enjoy exclusive content, including monthly Ask Me Anything (AMA) episodes, AMA transcripts, podcast episode transcripts, early access to live events and help advance human scientific research. Timestamps (00:00:00) Introduction (00:01:46) Why Is Fluoride in Water and Is It Harmful? (00:26:44) Huberman Lab Premium In the full AMA episode, we discuss: What Are the Effects of the Vagus Nerve on Calming the Body and the Brain? Title Card Photo Credit: Mike Blabac Disclaimer Learn more about your ad choices. Visit megaphone.fm/adchoices
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Folge vom 29.01.2024Tools to Enhance Working Memory & AttentionIn this episode, I discuss working memory, which is critical for learning and productivity, strategy setting, goal seeking, and navigating new environments. I explain the key role of dopamine and the biological mechanisms underlying working memory and how working memory differs from both short- and long-term memory. I also describe science-supported tools to enhance working memory and attention—including zero- or low-cost behavioral, supplemental and pharmacologic approaches. I include how to assess your working memory and how to use memory tasks to determine your baseline dopamine levels in certain brain circuits. This episode provides listeners with highly actionable tools to assess and improve their attention to specific tasks and task-switching capacity and to enhance their overall productivity. Read the full show notes for this episode at hubermanlab.com. Use Ask Huberman Lab, our chat-based tool, for summaries, clips, and insights from this episode. Thank you to our sponsors AG1: https://drinkag1.com/huberman LMNT: https://drinklmnt.com/hubermanlab Timestamps 00:00:00 Working Memory 00:01:12 Sponsors: Mateina, BetterHelp & Helix Sleep 00:05:00 Short- vs. Long-Term Memory 00:09:59 Neuroplasticity 00:15:42 Working Memory; Attention & Focus 00:20:04 Working Memory Test 00:25:35 Sponsor: AG1 00:27:02 Brain & Working Memory; Dopamine 00:36:13 Working Memory Capacity Test 00:44:37 Increasing Dopamine & Working Memory 00:49:26 Task Switching, Distractions 00:54:42 Sponsor: LMNT 00:56:04 Tool: Yoga Nidra, Non-Sleep Deep Rest (NSDR) & Dopamine 01:03:08 Tool: Deliberate Cold Exposure & Dopamine 01:11:02 Tool: Working Memory & Binaural Beats 01:15:23 Supplements to Increase Dopamine: L-Tyrosine, Mucuna Pruriens 01:22:53 Dopamine Prescriptions, Attention Deficit Hyperactivity Disorder (ADHD) 01:29:12 Zero-Cost Support, Spotify & Apple Reviews, YouTube Feedback, Sponsors, Momentous, Social Media, Neural Network Newsletter Disclaimer & Disclosures Learn more about your ad choices. Visit megaphone.fm/adchoices
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Folge vom 22.01.2024Journal Club with Dr. Peter Attia | Effects of Light & Dark on Mental Health & Treatments for CancerIn this journal club episode, my guest is Dr. Peter Attia, M.D., a Stanford and Johns Hopkins-trained physician focusing on healthspan and lifespan and the host of The Drive podcast. We each present a peer-reviewed scientific paper chosen because it contains novel, interesting, and actionable data. First, we discuss a paper on how bright light exposure at sunrise and throughout the day and dark exposure at night independently improve mental health and can offset some of the major symptoms of mental health disorders such as depression and anxiety. Then, we discuss an article that explores a novel class of immunotherapy treatments to combat cancer. We also discuss some of the new data on low-calorie sweeteners and if they are safe. This episode should be of interest to listeners curious about maximizing their vitality and longevity and to anyone seeking science-supported ways to improve mental health and lifespan. Read the full shotes for this episode at hubermanlab.com. Thank you to our sponsors AG1: https://drinkag1.com/huberman LMNT: https://drinklmnt.com/hubermanlab Timestamps 00:00:00 Dr. Peter Attia, Journal Club 00:02:56 Sponsors: LMNT & Waking Up 00:07:14 Light, Dark & Mental Health; Retina 00:11:16 Outdoor vs. Indoor Light, Cataracts, Sunglasses 00:16:17 Tools: Sunrise & Sunsets, Circadian Rhythm; Midday Light 00:24:55 Tools: Night & Light Exposure; Waking Before Sunrise 00:31:05 Article #1, Light/Dark Exposure & Mental Health 00:32:36 Sponsor: AG1 00:38:18 Odds Ratio, Hazard Ratio 00:45:43 Night vs. Daylight Exposure, Mental Health Disorders 00:51:35 Major Depression & Light Exposure; Error Bars & Significance 01:00:39 Prescriptions; Environmental & Artificial Light; Red Lights 01:08:14 Nighttime Light Exposure; Sleep Trackers & Belief Effects 01:13:54 Light Directionality, Phone, Night 01:17:21 Light Wavelengths & Sensors; Sunglasses 01:20:58 Hawthorne Effect, Reverse Causality, Genetics 01:26:26 Artificial Sweeteners, Appetite 01:31:16 Natural Light Cycles, Circadian Rhythm & Mental Health 01:39:53 Article #2, Immune System & Cancer 01:43:18 T-Cell Activation; Viruses 01:50:41 Autoimmunity; Cancer & Immune System Evasion 02:00:09 Checkpoint Inhibitors, CTLA-4 02:06:45 Anti-CTLA-4 Study Drug Ipilimumab, Melanoma 02:12:07 Patient Population, Randomization, GP100 02:18:09 Response Rate 02:22:52 Overall Survival & Response 02:28:38 Median Survival vs. Overall Survival, Drug Development 02:35:45 Gender & Dose 02:40:32 Adverse Events; Autoimmunity 02:46:42 Pancreatic Cancer; Aging & Immune System Health 02:53:57 Melanoma; Lynch Syndrome, Keytruda 02:58:43 Immunotherapy & Cancer Treatment; Melanoma Risk 03:06:26 Zero-Cost Support, Spotify & Apple Reviews, YouTube Feedback, Sponsors, Momentous, Social Media, Neural Network Newsletter Disclaimer & Disclosures Learn more about your ad choices. Visit megaphone.fm/adchoices
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Folge vom 15.01.2024Dr. Sean Mackey: Tools to Reduce & Manage PainIn this episode, my guest is Dr. Sean Mackey, M.D., Ph.D., Chief of the Division of Pain Medicine and Professor of Anesthesiology, Perioperative and Pain Medicine and Neurology at Stanford University School of Medicine. His clinical and research efforts focus on using advanced neurosciences, patient outcomes, biomarkers and informatics to treat pain. We discuss what pain is at the level of the body and mind, pain thresholds, and the various causes of pain. We also discuss effective protocols for controlling and reducing pain, including the use of heat and cold, acupuncture, chiropractic, physical therapy, nutrition, and supplementation. We also discuss how pain is influenced by our emotions, stress and memories, and practical tools to control one’s psychological perception of pain. And we discuss pain medications, including the controversial use of opioids and the opioid crisis. This episode will help people understand, manage, and control their pain as well as the pain of others. For show notes, including referenced articles and additional resources, please visit hubermanlab.com. Use Ask Huberman Lab, our new AI-powered platform, for a summary, clips, and insights from this episode. Thank you to our sponsors AG1: https://drinkag1.com/huberman LMNT: https://drinklmnt.com/hubermanlab Waking Up: https://wakingup.com/huberman Momentous: https://livemomentous.com/huberman Timestamps (00:00:00) Dr. Sean Mackey (00:02:28) Sponsors: LMNT & Waking Up (00:06:13) Pain, Unique Experiences, Chronic Pain (00:13:05) Pain & the Brain (00:16:15) Treating Pain, Medications: NSAIDs & Analgesics (00:22:46) Inflammation, Pain & Recovery; Ibuprofen, Naprosyn & Aspirin (00:27:51) Sponsor: AG1 (00:30:19) Caffeine, NSAIDs, Tylenol (00:32:34) Pain & Touch, Gate Control Theory (00:38:56) Pain Threshold, Gender (00:44:53) Pain in Children, Pain Modulation (Pain Inhibits Pain) (00:53:20) Tool: Heat, Cold & Pain; Changing Pain Threshold (01:00:54) Tools: Psychology, Mindfulness-Based Stress Reduction, Catastrophizing (01:08:29) Tool: Hurt vs. Harmed?, Chronic Pain (01:12:38) Emotional Pain, Anger, Medication (01:20:43) Tool: Nutrition & Pain; Food Sensitization & Elimination Diets (01:28:45) Visceral Pain; Back, Chest & Abdominal Pain (01:34:02) Referenced Pain, Neuropathic Pain; Stress, Memory & Psychological Pain (01:40:23) Romantic Love & Pain, Addiction (01:48:57) Endogenous & Exogenous Opioids, Morphine (01:53:17) Opioid Crisis, Prescribing Physicians (02:02:21) Opioids & Fentanyl; Morphine, Oxycontin, Methadone (02:07:44) Kratom, Cannabis, CBD & Pain; Drug Schedules (02:18:12) Pain Management Therapies, Acupuncture (02:22:19) Finding Reliable Physicians, Acupuncturist (02:26:36) Chiropractic & Pain Treatment; Chronic Pain & Activity (02:31:35) Physical Therapy & Chronic Pain; Tool: Pacing (02:36:35) Supplements: Acetyl-L-Carnitine, Alpha Lipoic Acid, Vitamin C, Creatine (02:42:25) Pain Management, Cognitive Behavioral Therapy (CBT), Biofeedback (02:48:32) National Pain Strategy, National Pain Care Act (02:54:05) Zero-Cost Support, Spotify & Apple Reviews, YouTube Feedback, Sponsors, Momentous, Social Media, Neural Network Newsletter Disclaimer Learn more about your ad choices. Visit megaphone.fm/adchoices