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In this episode, my guest is Natalie Crawford, MD, a double board-certified physician specializing in obstetrics and gynecology, fertility and reproductive health and host of the “As a Woman” podcast. We discuss female hormones, nutrition, supplementation, reproductive health, and fertility, including how the timing and duration of puberty impact a woman’s long-term hormone cycles and menopause. We also discuss the pros and cons of various birth control methods and how hormonal vs. non-hormonal birth control each affects fertility. We cover the factors that impact egg and sperm quality and how to leverage timing for conception. We also discuss procedures to assess female fertility, including egg count and hormone testing, the process of egg freezing, in vitro fertilization (IVF) and other reproductive options. This episode represents fairly comprehensive coverage of female hormones and reproductive health, highlighting important tests and screening, behavioral, nutritional, supplement and prescription-based tools that women of any age can use to improve their fertility, hormone function and overall health.  For show notes, including referenced articles and additional resources, please visit hubermanlab.com. Thank you to our sponsors AG1: https://drinkag1.com/huberman LMNT: https://drinklmnt.com/hubermanlab Waking Up: https://wakingup.com/huberman Momentous: https://livemomentous.com/huberman Timestamps (00:00:00) Dr. Natalie Crawford (00:01:52) Sponsors: LMNT & Waking Up (00:04:59) Female Puberty & Growth Characteristics, Height (00:13:27) Eggs & Ovulation, Harvesting Eggs, In Vitro Fertilization (IVF) (00:17:31) Endocrine Disruptors, Fetal Development (00:21:39) Lavender, Tea Tree & Evening Primrose Oils, Scents, Diapers (00:25:13) Breast Milk vs. Formula & Fertility (00:26:04) Menstruation Cycle & Hormones, Timing (00:33:47) Sponsor: AG1 (00:35:59) Estrogen, Progesterone & Menstrual Cycle (00:38:08) Hormonal Birth Control & Ovarian Reserve, AMH Testing, Fertility (00:42:42) Spermatogenesis & Testosterone; Heat: Ovaries vs Testes (00:46:11) Period & Pregnancy, Conception Window (00:48:56) Estrogen, Libido & Ovulation; Mittelschmerz (00:51:33) Tool: Intercourse Timing & Conception; Artificial Insemination, IVF (00:55:03) Egg/Sperm Quality, Cigarettes, Vaping, Cannabis & Alcohol  (01:03:29) Intrauterine Device (IUD), Depo-Provera & Fertility (01:10:00) Birth Control Risks & Benefits, Cancers, Polycystic Ovarian Syndrome (PCOS) (01:19:39) Blood Clotting & Birth Control Pill; Health Screening  (01:24:50) Tool: AMH Testing, Ovarian Reserve, Antral Follicle Count Ultrasound (01:29:55) IVF, In Vitro Maturation (IVM); Early Ovarian Reserve Screening (01:35:40) Tools: Egg Freezing, IVF; Age & Egg Quality (01:43:37) Egg Freezing & IVF Procedures, Maternal Age, Success Rates (01:51:30) Tool: Sperm Freezing & Paternal Age, Vasectomy (01:55:01) Hormones, Egg Freezing & IVF (02:00:42) Three-Parent IVF, Mitochondrial DNA (02:05:21) IVF Embryo Storage & Donation; Donor Education & Consent (02:14:29) Autism, Developmental Disorders, IVF Babies, Age  (02:20:36) Tools: Sleep, Nutrition & Fertility; Dietary Fat (02:27:32) Protein, Meat, Tofu, Fish; Sugar, Artificial Sweeteners; Weight & Miscarriage (02:37:38) Tools: Supplements; Prenatal Vitamins, Omega 3s, Vitamin D, Coenzyme Q10 (02:42:26) L-Carnitine & Male Fertility; PCOS & Myo-inositol; Metformin (02:47:11) Egg Retrieval, Ovarian Hyperstimulation Syndrome, Minimal Stimulation (02:57:56) INVOcell (03:03:12) Egg Freezing, Intracytoplasmic Sperm Injection (ICSI), Sperm Fragmentation (03:11:45) Genetic Testing, IVF Transfer & Success Rate, Embryo Banking (03:15:10) Menopause (03:19:47) Hormone Replacement Therapy & Menopause (03:22:25) Early-signs of Menopause (03:25:18) Zero-Cost Support, Spotify & Apple Reviews, Sponsors, YouTube Feedback, Momentous, Social Media, Neural Network Newsletter Disclaimer Learn more about your ad choices. Visit megaphone.fm/adchoices

In this episode, my guest is Dr. Michael Eisenberg, MD, a urologist and professor specializing in male sexual function and fertility at Stanford University. Based on his clinical work and research, he is considered a top world expert on male sexual and reproductive health. We discuss testosterone levels and what really impacts them, testosterone therapy, sperm quality and counts, penile and testicular health and function, pelvic floor and prostate and urinary tract health, erectile function and dysfunction and the various causes and treatments for common male sexual, hormonal and reproductive challenges. We also address post-finasteride syndrome and trends in penile length. This episode is rich in actionable information about men’s sexual and reproductive health, including key tests and at-home evaluations, and the behavioral, nutritional, exercise and prescription-based tools that can support male sexual and reproductive health. For show notes, including referenced articles and additional resources, please visit hubermanlab.com. Use Ask Huberman Lab, our new AI-powered platform, for a summary, clips, and insights from this episode. Thank you to our sponsors AG1: https://drinkag1.com/huberman LMNT: https://drinklmnt.com/hubermanlab Waking Up: https://wakingup.com/huberman Momentous: https://livemomentous.com/huberman Timestamps (00:00:00) Dr. Michael Eisenberg (00:02:05) Sponsors: LMNT & Waking Up (00:04:20) Sperm Quality, Geographic & Environmental Factors  (00:12:00) Fertility & Sperm Quality; Testosterone, Cell Phones & Heat (00:19:26) Testosterone, Age, Obesity (00:26:49) Tool: Optimize Sperm Quality, Exogenous Testosterone, hCG (00:35:56) Sponsor: AG1 (00:36:57) Tool: Lifestyle Factors & Sperm Quality, Alcohol (00:43:27) Sperm Quality, Recreational & Over-the-Counter Drugs, Cannabis (00:46:56) High-Impact Sports, Traumatic Brain Injury (TBI), Pituitary & Testosterone (00:49:55) Bicycling, Numbness & Sexual Dysfunction; Walking & Testosterone (00:55:39) Exogenous Testosterone Therapy & Cancer (00:59:57) Sexual & Urinary Health, Nighttime Urination (01:03:12) Sleep & Semen Quality; Overall Health (01:09:19) Tool: Sperm Analysis & Overall Health; Sperm Banking (01:13:21) Paternal Age & Puberty Trends; Older Fathers & Child Health Risk (01:26:42) Tool: Prostate Health, Urination; Tadalafil (Cialis) (01:33:02) Urinary Tract Infections (UTIs); Erectile Dysfunction Causes (01:38:21) Blood Flow & Erectile Dysfunction, Medication; Cardiovascular Health (01:44:30) Mechanical Erectile Dysfunction Treatments; Peptides; Delayed Ejaculation (01:52:36) Pelvic Floor Health, Urology & Physical Therapy; Split-Stream Urination (01:59:03) Penile Length & Trends; Dihydrotestosterone (DHT), Puberty (02:09:01) Hair Loss, Dutasteride, Finasteride & Sexual Health; Post-Finasteride Syndrome (02:16:11) Clomiphene, Testosterone & Estrogen Signaling (02:19:31) Follicle-Stimulating Hormone (FSH) Therapy; Prolactin, Estrogen (02:24:15) Varicocele; Peyronie’s Disease (02:27:26) Testis & Cancer Risk; Insurance, Blood Profiles & Semen Analysis (02:35:03) Zero-Cost Support, Spotify & Apple Reviews, Sponsors, YouTube Feedback, Momentous, Social Media, Neural Network Newsletter Disclaimer Learn more about your ad choices. Visit megaphone.fm/adchoices

Welcome to a preview of the 12th Ask Me Anything (AMA) episode, part of Huberman Lab Premium. The Huberman Lab Premium subscription was launched for two main reasons. First, it was launched in order to raise support for the standard Huberman Lab podcast channel — which will continue to come out every Monday at zero-cost. Second, it was launched as a means to raise funds for important scientific research. A significant portion of proceeds from the Huberman Lab Premium subscription will fund human research (not animal models) selected by Dr. Huberman, with a dollar-for-dollar match from the Tiny Foundation. If you're an existing Premium member, you can login to access the full episode. If you're not a member, you can join Huberman Lab Premium to enjoy exclusive content, including monthly Ask Me Anything (AMA) episodes, AMA transcripts, podcast episode transcripts, early access to live events and help advance human scientific research. Timestamps (00:00:00) Introduction (00:01:46) Resveratrol and Longevity Supplements (00:26:49) Huberman Lab Premium In the full AMA episode, we discuss: What Is Working Memory and How to Improve It Title Card Photo Credit: Mike Blabac Disclaimer Learn more about your ad choices. Visit megaphone.fm/adchoices