Science Friday Folgen

Researchers continue to test out new ways to use artificial intelligence in medicine.Some research shows that AI is better at reading mammograms than radiologists. AI can predict and diagnose disease by analyzing the retina, and there’s even some evidence that GPT-4 might be helpful in making challenging diagnoses, ones missed by doctors.However, these applications can come with trade-offs in security, privacy, cost, and the potential for AI to make medical mistakes.Ira and guest host Sophie Bushwick talk about the role of AI in medicine and take listener calls with Dr. Eric Topol, founder and director of the Scripps Research Translational Institute and professor of molecular medicine, based in La Jolla, California.Transcripts for each segment will be available after the show airs on sciencefriday.com. Subscribe to this podcast. Plus, to stay updated on all things science, sign up for Science Friday's newsletters.

This week, a research team in China reported that it had successfully cloned a rhesus monkey, which has lived normally for over two years and reached maturity. It marks the first time that a rhesus monkey has been successfully cloned. Rhesus monkeys are used widely in medical research, making the advance potentially useful for medical trials.Cloning of primates in general has been difficult. Six years ago researchers cloned long-tailed macaques using the technique originally used for Dolly the cloned sheep. But an attempt to use that approach to clone a rhesus was unsuccessful, producing an animal that died after 12 hours. In the new work, the research team identified flaws in placental cells of previous cloned embryos. To address those flaws, they replaced the outer trophoblast cells from a developing cloned embryo with ones from an embryo created through an in-vitro fertilization technique—essentially providing cells that would develop into a normal placenta for the cloned embryo.Tim Revell of New Scientist joins Ira to talk about the work and its implications. They’ll also discuss other stories from the week in science, including the discovery of lots of ice buried under Mars’ equator, an AI that’s good at solving high school math challenges, and the discovery of four new species of octopus.Transcripts for each segment will be available the week after the show airs on sciencefriday.com Subscribe to this podcast. Plus, to stay updated on all things science, sign up for Science Friday's newsletters.

In October 2023, an international group of scientists released an impressively detailed cell atlas of the human brain, published in 21 papers in the journals Science, Science Advances and Science Translational Medicine.The human brain has roughly 171 billion cells, which makes it a herculean task to categorize them all. Scientists collected samples from different parts of the brain and have identified 3,000 different types of cells. Each cell contains thousands of genes and each cell type only expresses a small fraction of those. Cataloging cells by their gene expressions, paves the way for scientists to tailor disease treatments to target only the affected cells. This human brain cell atlas is only the first draft, but it could signal a paradigm shift in how we understand and treat neurological diseases.Ira talks with one of the researchers who helped put together the cell atlas, Dr. Ed Lein, senior investigator at the Allen Institute for Brain Science, and takes listener calls.Transcripts for each segment will be available the week after the show airs on sciencefriday.com. Subscribe to this podcast. Plus, to stay updated on all things science, sign up for Science Friday's newsletters.