Science Friday Folgen

A Replacement Heart, From A Pig This week, doctors reported that they had successfully transplanted a heart taken from a pig into a human being, a type of procedure known as xenotransplantation. The pig had been genetically modified to lack a certain protein thought to be responsible for organ rejection in previous transplant attempts. The patient, a 57 year-old man, will be monitored for any sign of rejection or infection with a porcine virus—but doctors are hopeful that the work will lead to further transplants and a new source of replacement organs for people. Science journalist Roxxane Kamsi joins Ira to talk about that and other stories from the week in science, including research into how antivirals work in people infected with HIV, the role of clothes dryers on microplastics pollution, a push to make the U.S. electric grid greener, and more.   Omicron Sparks Surge In Pediatric Hospitalizations Omicron’s rapid spread has many parents and caregivers of young children on edge. The most recent CDC data shows 5.3 cases per 100,000 children under four are hospitalized with COVID-19 in the United States, the highest number since the pandemic started. And kids under five still aren’t eligible to be vaccinated. When word went out that we were going to answer questions about COVID and kids, we were flooded with questions from our listeners. To help answer some of those questions, and better understand how to keep our kids safe, Ira spoke with Dr. Yvonne Maldonado, pediatrician, and professor of global health and infectious diseases at Stanford University, and Dr. Rick Malley, infectious diseases specialist at Boston Children’s Hospital and professor of pediatrics at Harvard Medical School.   Ivermectin’s False Reputation Exemplifies How Misinformation Spread Not a single scientific or health authority in the U.S. recommends the use of the anti-parasitic drug ivermectin to treat or prevent COVID-19. Still, some Americans see the unproven drug as a way out of the pandemic. Ivermectin is mostly used in large animals and is approved by the U.S. Food and Drug Administration for treating human conditions, including head lice and stomach worms. But across the country, demand for the drug has surged in recent months — leading to a spike in hospitalizations for human exposures to ivermectin. The drug is among the latest politically divisive public health issues unfolding across the country. The situation has fast-tracked conversations about the risks and benefits of publicizing research findings that have not yet been vetted by the scientific community. That’s because much of the misinformation on ivermectin draws on insufficient data — some coming from low-quality studies, including ones that were retracted after further examination revealed problems and even potential fraud. Read the rest at sciencefriday.com. A Massive New Find Of Icefish Found Near Antarctic The frigid waters near Antarctica are home to an unusual family of fishes collectively known as the icefish. They have translucent blood, white hearts, and have adapted to live without red blood cells or hemoglobin, relying instead on copper compounds that function better at low temperatures. Now, researchers mapping the floor of the Weddell Sea report in the journal Current Biology that they have spotted a massive colony of the unusual sea creatures—containing over 60 million icefish nests. “A few dozen nests have been observed elsewhere in the Antarctic, but this find is orders of magnitude larger,” said Autun Purser, of the Alfred Wegener Institute in Bremerhaven, Germany. Purser and his colleagues were mapping the seafloor of the Filchner ice shelf region, in an area of thermal upwelling, where there are slightly warmer temperatures. They found masses of icefish nests clumped close together as far as the eye can see, somewhat like a land-based colony of nesting penguins. Purser joins Ira to talk about the discovery, and what’s known about the ultra-cold ecosystems of Antarctic seas.     Subscribe to this podcast. Plus, to stay updated on all things science, sign up for Science Friday's newsletters.

Omicron Variant Drives Winter COVID Surge The United States set a global record this week, recording roughly one million new coronavirus tests in a single day. The current surge in cases is mostly driven by Omicron. The highly contagious variant accounted for about 95% of new cases last week. And, to top it all off, tests are in short supply, the CDC changed its quarantine guidelines, and some schools have returned to remote learning. Virologist Angela Rasmussen joins Ira to help make sense of the latest deluge of Omicron news. Rasmussen is a research scientist at VIDO-InterVac, the University of Saskatchewan’s vaccine research institute in Saskatoon, Saskatchewan.   Is Omicron A Less Severe Variant Of COVID-19? Over the past few weeks, a common refrain has popped up in reports about the Omicron variant of COVID-19: The variant seems to be “less severe” than earlier forms of the virus. But as hospitals fill up with coronavirus patients and infections skyrocket, there’s some context needed to understand what the full impact of a less-severe variant might be. An important recent discovery sheds light on the severity of the variant, finding that at least in hamsters, Omicron spares the lungs in a way earlier variants have not. This infection appears to be predominantly in the upper respiratory system, largely in the mouth, throat, and windpipe. But even though a fewer percentage of cases may experience severe disease than with earlier variants, the sheer volume may still threaten hospital capacities. Joining Ira to talk about the severity of the Omicron variant in the body is Dr. Michael Diamond, virologist, and immunologist at the Washington University School of Medicine in St. Louis. Also joining the conversation to talk about Omicron’s toll on the healthcare system is Dr. Saskia Popescu, infectious disease epidemiologist and infection prevention expert at the University of Arizona College of Public Health in Phoenix, Arizona.   How Christmas Bird Counts Help Shape Science This winter marks the 122nd annual Christmas Bird Count, a project of the National Audubon Society, which is self-described as the longest-running community science project in the country. What started as a few dozen volunteers in 1900 has grown to tens of thousands of birders, spreading out in 15-mile circles across the country to count every bird insight on one midwinter day. From this record, scientists can draw insights about everything from the abundance of species to how species’ ranges are shifting from year-to-year and decade-to-decade. Ira talks to Audubon’s bird count director Geoff LeBaron, and director of quantitative science Nicole Michel about the value of the annual community science project and some of their more joyful winter sightings. Plus, how the data provide clues to which birds are most likely to adapt as human habitat disruption and climate change continue.   Subscribe to this podcast. Plus, to stay updated on all things science, sign up for Science Friday's newsletters.

How A Former Microsoft Exec Mastered The Perfect Slice—Using Science Who doesn’t love pizza? It’s a magical combination of sauce, cheese, crust, and maybe even a topping or two. Depending on where you eat it, the ratio of sauce and cheese and toppings changes: Neapolitan, NY Style, and Chicago Deep Dish each have a slightly different recipe. And different methods of baking impart their signature flavor on the end result—whether that’s coal, wood, or gas-fired ovens. Nearly every country in the world has some type of variation on the classic. Author Nathan Myhrvold visited over 250 pizzerias all over the world to appreciate their differences. Then he made over 12,000 pizzas, using physics and chemistry to tweak each one slightly. Myhrvold and his co-author, chef Francisco Migoya wrote all about the gourmand experiment in a three-volume, 35-pound set of beautifully illustrated and painstakingly researched books. Ira talks with Nathan Myhrvold, former CTO at Microsoft, founder of Intellectual Ventures and Modernist Cuisine about his discoveries and his most recent book, Modernist Pizza. E.O. Wilson’s Indelible Mark On Ecology Ecologist and ant biologist Edward O. Wilson (often called E. O. Wilson) died December 26, at the age of 92. Though he was known for his study of ants and their social behavior, his impact extended much further—from sociobiology, the study of the influence of genetics on behavior, to the way science was taught and understood. His writing twice won the Pulitzer Prize. Wilson appeared on Science Friday many times. In this short remembrance of Wilson, Ira replays selections from past conversations with the scientist, recorded between 2006 and 2013.   The Fossil—And Family—Records Of Richard Leakey Paleoanthropologist Richard Leakey died on January 2 at the age of 77. The Kenyan conservationist and fossil hunter was the son of paleoanthropologists Louis and Mary Leakey, who helped redefine the early parts of the human family tree. Richard was part of the team that discovered ‘Turkana Boy,’ a Homo erectus skeleton—one of the most complete early hominin skeletons ever found. In later years, he was the director of the National Museum of Kenya, the head of the Kenya Wildlife Service, helped found a political party, and led the Kenyan Civil Service in the midst of an anti-corruption campaign. In this edited interview from 2011, Leakey describes his work in the field, his famous fossil-hunting lineage, and his desire to convince skeptics of the reality of human evolution.   Subscribe to this podcast. Plus, to stay updated on all things science, sign up for Science Friday's newsletters.