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Paul Farmer, Global Health Leader, Dies At 62 Paul Farmer, physician and co-founder of the humanitarian medical organization Partners in Health died unexpectedly this week in Rwanda at the age of 62. Farmer was widely known for his compassion, and his conviction that all people around the world, regardless of their means, deserved access to quality medical treatments and interventions. Sarah Zhang, staff writer at The Atlantic, joins John Dankosky to remember Paul Farmer and his work around the world, from Haiti to Peru to Russia. They also discuss concern over a possible re-emergence of wild polio in Malawi, a new U.N. report linking climate change to a potential increase in wildfires around the world, and the case of Hank the Tank—a burly bear troubling Lake Tahoe. We’ll also get an update on the tale of a wayward piece of space junk soon to impact the moon, and dive into the link between Epstein-Barr virus and multiple sclerosis. We recently discussed research establishing the link between the two conditions—and now there is new work looking at the possible mechanism of the connection.   Blind Patients With Eye Implant Left In The Dark As Its Startup Struggles Barbara Campbell was walking through a New York City subway station during rush hour when her world abruptly went dark. For four years, Campbell had been using a high-tech implant in her left eye that gave her a crude kind of bionic vision, partially compensating for the genetic disease that had rendered her completely blind in her 30s. “I remember exactly where I was: I was switching from the 6 train to the F train,” Campbell tells IEEE Spectrum. “I was about to go down the stairs, and all of a sudden I heard a little ‘beep, beep, beep’ sound.’” It wasn’t her phone battery running out. It was her Argus II retinal implant system powering down. The patches of light and dark that she’d been able to see with the implant’s help vanished. Terry Byland is the only person to have received this kind of implant in both eyes. He got the first-generation Argus I implant, made by the company Second Sight Medical Products, in his right eye in 2004, and the subsequent Argus II implant in his left 11 years later. He helped the company test the technology, spoke to the press movingly about his experiences, and even met Stevie Wonder at a conference. “[I] went from being just a person that was doing the testing to being a spokesman,” he remembers. Yet in 2020, Byland had to find out secondhand that the company had abandoned the technology and was on the verge of going bankrupt. While his two-implant system is still working, he doesn’t know how long that will be the case. “As long as nothing goes wrong, I’m fine,” he says. “But if something does go wrong with it, well, I’m screwed. Because there’s no way of getting it fixed.”   Read the rest at sciencefriday.com.   Climate Change Ruins The World Championship Sled Dog Derby Teams of sled dogs and mushers from across the United States and Canada visited Laconia this weekend for the 93rd annual World Championship Sled Dog Derby. Racers were in good spirits, though they faced slushy conditions on Friday and Saturday—a situation that has become more common, many mushers said, as climate change causes winters to warm. Vince Buoniello was the chief judge for the Laconia race, which has a deep and prestigious history in the sled dog world. He likened it to the Super Bowl. “Laconia was always a magic name. Everybody wanted to race Laconia,” he said. Through his 65 years in the sled dog world, Buoniello has seen big changes—fewer people seem to be involved in the sport, and it’s harder to find undeveloped land for sledding trails. And, he said, warming winters have made races difficult to schedule. “We raced every weekend for years and years. It was an exception if a race ever got canceled. Now, forget it. It’s changed drastically,” he said. “To see mud, it just blows your mind. It just never used to happen.” Buoniello, who is 90, said judging the race in the warm conditions had tired him out a bit. But, he said, his love for the sport and the animals has made it worthwhile throughout his career. “The dogs kept me going,” he said. “It was just such love. It was just pure love.” Read the rest at sciencefriday.com.   An Elusive Search For Freedom From Human-Made Noise If you stand in the middle of a busy street in New York City and listen to the sounds around you, you’re hearing what Bernie Krause calls “the anthropophony.” It’s the cacophony of “incoherent and chaotic” noise that’s drawing people away from the natural world. “In fact, the further we draw away from the natural world, the more pathological we become as a culture,” he said. Krause has been charting this change for more than 50 years, as one of the world’s foremost chroniclers of nature sounds. He’s recorded more than 15,000 species and their habitats. In his new book, The Power of Tranquility in a Very Noisy World, he makes the case that human-made noise is causing us stress. Krause offers a simple prescription: “Shut the hell up,” and listen to the soundscapes of nature, what he calls “the biophony.” “If we listen to sounds of the natural world, for example, which are the original soundscapes that we were exposed to, it’s very restorative and therapeutic,” he said. Read the rest at sciencefriday.com.     Subscribe to this podcast. Plus, to stay updated on all things science, sign up for Science Friday's newsletters.

New Device Helps People With Paralysis Walk Again Spinal cord injuries are notoriously difficult to treat, especially for those who have been paralyzed for several years. Now, researchers have developed a new implant that is able to reverse paralysis in patients with complete spinal cord injuries. The device uses specially designed electrodes, which bring the brain back into communication with the patient’s lower body. The findings were recently published in the academic journal Nature Medicine. Ira talks with the study’s co-authors, Jocelyne Bloch, a neurosurgeon at Lausanne University Hospital, and Grégoire Courtine, professor of neuroscience at the Swiss Federal Institute of Technology, based in Lausanne, Switzerland.   Could Protein-Based Vaccines Help Close The Global Vaccination Gap? A new generation of COVID-19 vaccines are being developed and distributed around the world. They’re called recombinant-protein vaccines. But the tech is actually not at all new. In fact, It’s been used to produce hepatitis C and pertussis vaccines for decades. These protein-based vaccines have an edge over mRNA vaccines in a few ways. They’re just as effective, cheaper and simpler to manufacture, and easier to distribute. So why, two years into the pandemic, have they just started gaining traction? And can recombinant-protein vaccines help close the global coronavirus vaccination gap? Ira discusses these developments with Dr. Maria Elena Bottazzi, the co-creator of Corbevax, a patent-free protein-based vaccine, for which she was recently nominated for the Nobel Peace Prize. She’s also the co-director of the Center for Vaccine Development at Texas Children’s Hospital, and a professor at the Baylor College of Medicine, based in Houston, Texas.   How Cuba Developed Five COVID-19 Vaccines Cuba was able to quickly produce five coronavirus vaccines, thanks to the island’s robust biotech industry. For decades, Cuba has produced its own home-grown vaccines and distributed them to neighboring countries. But sanctions and political dynamics have complicated Cuba’s ability to distribute their COVID-19 vaccines with the world. Ira talks with Helen Yaffe, senior lecturer of economic and social history at Glasgow University, and author of We Are Cuba! How a Revolutionary People Have Survived in a Post-Soviet World.   Fish Make More Noise Than You Think One of the most famous films of undersea explorer Jacques Cousteau was titled The Silent World. But when you actually stop and listen to the fishes, the world beneath the waves is a surprisingly noisy place. In a recent study published in the journal Ichthyology & Herpetology, researchers report that as many of two-thirds of the ray-finned fish families either are known to make sounds, or at least have the physical capability to do so. Some fish use specialized muscles around their buoyancy-modulating swim bladders to make noise. Others might blow bubbles out their mouths, or, in the case of herring, out their rear ends, producing “fish farts.” Still other species use ridges on their bodies to make noises similar to the way crickets do, grind their teeth, or snap a tendon to sound off. The noises serve a variety of purposes, from calling for a mate to warning off an adversary. Aaron Rice, principal ecologist in the K. Lisa Yang Center for Conservation Bioacoustics at the Cornell Lab of Ornithology in Ithaca, walks Ira through some of the unusual sounds produced by known fish around the world—and some mystery noises that they know are produced by fish, but have yet to identify.     Subscribe to this podcast. Plus, to stay updated on all things science, sign up for Science Friday's newsletters.

Third Person Cured From HIV, Thanks To Umbilical Cord Stem Cells The third person ever, and the first woman, has been cured of the HIV virus, thanks to a stem cell transplant using umbilical cord blood. While the invasive, risky bone marrow transplant process may not prove the answer for large numbers of people, the use of cord blood may open up pathways to new treatment options for a wider variety of people than the adult stem cells used to cure the two previous patients. Vox staff writer Umair Irfan explains why. Plus how President Biden is using executive orders for decarbonizing new parts of the economy, new research on the climate origins of the mega-drought in the American West, a prediction for even more rapidly rising sea levels from NOAA, and how orangutans—some of them at least—might be able to use tools.   How To Close Gaps In Healthcare Access When a public health crisis strikes, a natural instinct is to turn to a strong leader. The COVID-19 pandemic is a prime example: We want someone who can calm our fears, tell us what to expect, and what steps we can take to make things better. But leadership does not happen overnight—and it will take a brave person to step into the shoes that guide the country through the next stage of the pandemic. Dr. David Satcher is used to adversity. Born into poverty in Anniston, Alabama, Satcher contracted whooping cough at two years old. The town’s only Black doctor, Dr. Jackson, treated Satcher, but did not expect him to live. Overcoming this illness launched him into a lifetime of public health work, with an emphasis on health equity. Satcher speaks to Ira about his work as former assistant secretary for health, surgeon general of the U.S., and director of the Centers for Disease Control under Presidents Bill Clinton and George W. Bush. They also discuss his leadership work at the Morehouse School of Medicine, and his advice for getting the country towards a more equitable healthcare system.   New Energy Record Set By Fusion Reactor The promise of a human-made, sustained, controlled nuclear fusion reaction has always seemed to be “just a few decades away.” But now recent results from JET, the Joint European Torus experiment, have researchers hopeful that practical fusion may indeed be possible as soon as 2035. In the experiment, a high-temperature plasma made of equal parts deuterium and tritium was confined in a magnetic containment vessel known as a tokamak. The run produced 59 megajoules of energy over a fusion “pulse” of five seconds, considerably longer than previous attempts. While the experiment did not produce more energy than it took to produce the extreme conditions needed to induce fusion, researchers took the run as a proof of concept that an upcoming reactor called ITER should be successful. Alain Bécoulet, head of the engineering domain for the ITER project and author of the upcoming book Star Power: ITER and the International Quest for Fusion Energy joins Ira to discuss the recent advance at JET and the prospects for producing a sustained, controlled nuclear fusion reaction—what Bécoulet calls mastering a small piece of the sun.   Subscribe to this podcast. Plus, to stay updated on all things science, sign up for Science Friday's newsletters.