Science Friday Folgen

It’s common knowledge that many diseases and conditions have some kind of genetic link. But that wasn't always the case. In 1990, long before the Human Genome Project tied so many health issues to differences in genetics, researchers identified a gene called BRCA1. It was the first gene linked to a hereditary form of any common cancer. People with certain variants of BRCA1 stood a higher risk of developing breast and ovarian cancer than those without those mutations.   Geneticist Mary-Claire King and her lab were the first to identify that gene. She joined Host Flora Lichtman in September 2025 to talk about her background, her research, and her approach to science. Guest: Dr. Mary-Claire King is an American Cancer Society Professor in the departments of Genome Sciences and Medicine at the University of Washington in Seattle. Other episodes you may enjoy: A Nagasaki Survivor And Physician Recounts His Life’s Work I Was Considered A Nobody Transcripts for each episode are available within 1-3 days at sciencefriday.com. Subscribe to this podcast. Follow our show on Instagram, TikTok, Facebook, and Bluesky @scifri and sign up for our newsletters. Got a science question that’s keeping you up at night? Call us: 877-472-4374 Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

Old creepy houses are a horror cliche, but why? Why do they freak us out? According to new research, it might have something to do with infrasound: a sound that’s below the range of human hearing, potentially emitted by low-rumbling pipes or old boilers more common in older houses.   Psychologist and pseudoscience researcher Rodney Schmaltz explains his new study, and what role infrasound could play in leading people to feel unsettled in “haunted” places. Then, infrasound researcher Milton Garcés breaks down the infrasound that’s produced by volcanoes and asteroid impacts, and how it serves as a “keep away” signal in nature. Guests: Dr. Rodney Schmaltz is a professor of psychology at MacEwan University in Edmonton, Alberta. Dr. Milton Garcés is a research scientist at the Hawai‘i Institute of Geophysics and Planetology and director of the Infrasound Laboratory at the University of Hawai’i in Honolulu. Other episodes you may enjoy: What The Sounds Of Melting Glaciers Can Tell Us The World According To Sound: A Sonic History Of Astronomy Transcripts for each episode are available within 1-3 days at sciencefriday.com. Subscribe to this podcast. Follow our show on Instagram, TikTok, Facebook, and Bluesky @scifri and sign up for our newsletters. Got a science question that’s keeping you up at night? Call us: 877-472-4374 Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

We recently got a call from a SciFri listener in Florida who has autoimmune arthritis. He told us that over the years he’d taken 10 drugs, and each out eventually stopped working. He then tried to enroll in a clinical trial for a new drug for his condition, but he was rejected specifically because he was on his 10th drug. Today we’re digging into clinical trials and how they work. Are there incentives for drug developers to leave out “problem children”? Or is it more complicated than that? Flora talks with lawyer and bioethicist Holly Fernandez Lynch about what clinical trials are designed to do, how participants are chosen, and where FDA regulation comes into play. Guest: Dr. Holly Fernandez Lynch is an associate professor of medical ethics and health policy at the University of Pennsylvania. Other episodes you may enjoy: Why so many studies can’t be replicatedCan ‘Suggestion-Box Science’ Make Public Health More Useful? Transcripts for each episode are available within 1-3 days at sciencefriday.com. Subscribe to this podcast. Follow our show on Instagram, TikTok, Facebook, and Bluesky @scifri and sign up for our newsletters. Got a science question that’s keeping you up at night? Call us: 877-472-4374 Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.